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Understanding metric-related pitfalls in image analysis validation.

Publication ,  Journal Article
Reinke, A; Tizabi, MD; Baumgartner, M; Eisenmann, M; Heckmann-Nötzel, D; Kavur, AE; Rädsch, T; Sudre, CH; Acion, L; Antonelli, M; Arbel, T ...
Published in: Nature methods
February 2024

Validation metrics are key for tracking scientific progress and bridging the current chasm between artificial intelligence research and its translation into practice. However, increasing evidence shows that, particularly in image analysis, metrics are often chosen inadequately. Although taking into account the individual strengths, weaknesses and limitations of validation metrics is a critical prerequisite to making educated choices, the relevant knowledge is currently scattered and poorly accessible to individual researchers. Based on a multistage Delphi process conducted by a multidisciplinary expert consortium as well as extensive community feedback, the present work provides a reliable and comprehensive common point of access to information on pitfalls related to validation metrics in image analysis. Although focused on biomedical image analysis, the addressed pitfalls generalize across application domains and are categorized according to a newly created, domain-agnostic taxonomy. The work serves to enhance global comprehension of a key topic in image analysis validation.

Duke Scholars

Published In

Nature methods

DOI

EISSN

1548-7105

ISSN

1548-7091

Publication Date

February 2024

Volume

21

Issue

2

Start / End Page

182 / 194

Related Subject Headings

  • Developmental Biology
  • Artificial Intelligence
  • 31 Biological sciences
  • 11 Medical and Health Sciences
  • 10 Technology
  • 06 Biological Sciences
 

Citation

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MLA
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Reinke, A., Tizabi, M. D., Baumgartner, M., Eisenmann, M., Heckmann-Nötzel, D., Kavur, A. E., … Maier-Hein, L. (2024). Understanding metric-related pitfalls in image analysis validation. Nature Methods, 21(2), 182–194. https://doi.org/10.1038/s41592-023-02150-0
Reinke, Annika, Minu D. Tizabi, Michael Baumgartner, Matthias Eisenmann, Doreen Heckmann-Nötzel, A Emre Kavur, Tim Rädsch, et al. “Understanding metric-related pitfalls in image analysis validation.Nature Methods 21, no. 2 (February 2024): 182–94. https://doi.org/10.1038/s41592-023-02150-0.
Reinke A, Tizabi MD, Baumgartner M, Eisenmann M, Heckmann-Nötzel D, Kavur AE, et al. Understanding metric-related pitfalls in image analysis validation. Nature methods. 2024 Feb;21(2):182–94.
Reinke, Annika, et al. “Understanding metric-related pitfalls in image analysis validation.Nature Methods, vol. 21, no. 2, Feb. 2024, pp. 182–94. Epmc, doi:10.1038/s41592-023-02150-0.
Reinke A, Tizabi MD, Baumgartner M, Eisenmann M, Heckmann-Nötzel D, Kavur AE, Rädsch T, Sudre CH, Acion L, Antonelli M, Arbel T, Bakas S, Benis A, Buettner F, Cardoso MJ, Cheplygina V, Chen J, Christodoulou E, Cimini BA, Farahani K, Ferrer L, Galdran A, van Ginneken B, Glocker B, Godau P, Hashimoto DA, Hoffman MM, Huisman M, Isensee F, Jannin P, Kahn CE, Kainmueller D, Kainz B, Karargyris A, Kleesiek J, Kofler F, Kooi T, Kopp-Schneider A, Kozubek M, Kreshuk A, Kurc T, Landman BA, Litjens G, Madani A, Maier-Hein K, Martel AL, Meijering E, Menze B, Moons KGM, Müller H, Nichyporuk B, Nickel F, Petersen J, Rafelski SM, Rajpoot N, Reyes M, Riegler MA, Rieke N, Saez-Rodriguez J, Sánchez CI, Shetty S, Summers RM, Taha AA, Tiulpin A, Tsaftaris SA, Van Calster B, Varoquaux G, Yaniv ZR, Jäger PF, Maier-Hein L. Understanding metric-related pitfalls in image analysis validation. Nature methods. 2024 Feb;21(2):182–194.

Published In

Nature methods

DOI

EISSN

1548-7105

ISSN

1548-7091

Publication Date

February 2024

Volume

21

Issue

2

Start / End Page

182 / 194

Related Subject Headings

  • Developmental Biology
  • Artificial Intelligence
  • 31 Biological sciences
  • 11 Medical and Health Sciences
  • 10 Technology
  • 06 Biological Sciences