Molecular genetics: toward an understanding of childhood cancer.
Publication
, Journal Article
Kreissman, SG
Published in: Semin Pediatr Surg
February 1993
Investigation in cellular and molecular genetics has yielded a wealth of new information regarding the role of genetic alterations in the etiology of childhood cancer. The recent advancement of molecular biologic techniques has allowed researchers to bridge the gap from the description of chromosomal aberrations in tumor cells to the current identification of oncogenes and tumor suppressor genes involved in malignant transformation. This article reviews the advances in molecular genetics of childhood cancer, briefly outlines the history, and details the current knowledge of the use of cytogenetics, oncogenes, and other tools in the diagnosis, management, and further understanding of pediatric malignancies.
Duke Scholars
Published In
Semin Pediatr Surg
ISSN
1055-8586
Publication Date
February 1993
Volume
2
Issue
1
Start / End Page
2 / 10
Location
United States
Related Subject Headings
- Prognosis
- Pediatrics
- Oncogenes
- Neoplasms
- Molecular Biology
- Humans
- Genes, Tumor Suppressor
- Chromosome Aberrations
- Child
- Cell Transformation, Neoplastic
Citation
APA
Chicago
ICMJE
MLA
NLM
Kreissman, S. G. (1993). Molecular genetics: toward an understanding of childhood cancer. Semin Pediatr Surg, 2(1), 2–10.
Kreissman, S. G. “Molecular genetics: toward an understanding of childhood cancer.” Semin Pediatr Surg 2, no. 1 (February 1993): 2–10.
Kreissman SG. Molecular genetics: toward an understanding of childhood cancer. Semin Pediatr Surg. 1993 Feb;2(1):2–10.
Kreissman, S. G. “Molecular genetics: toward an understanding of childhood cancer.” Semin Pediatr Surg, vol. 2, no. 1, Feb. 1993, pp. 2–10.
Kreissman SG. Molecular genetics: toward an understanding of childhood cancer. Semin Pediatr Surg. 1993 Feb;2(1):2–10.
Published In
Semin Pediatr Surg
ISSN
1055-8586
Publication Date
February 1993
Volume
2
Issue
1
Start / End Page
2 / 10
Location
United States
Related Subject Headings
- Prognosis
- Pediatrics
- Oncogenes
- Neoplasms
- Molecular Biology
- Humans
- Genes, Tumor Suppressor
- Chromosome Aberrations
- Child
- Cell Transformation, Neoplastic