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Caudate hyperintensities in elderly depressed patients with neuroleptic-induced parkinsonism.

Publication ,  Journal Article
Figiel, GS; Krishnan, KR; Doraiswamy, PM; Nemeroff, CB
Published in: J Geriatr Psychiatry Neurol
1991

Elderly patients are particularly sensitive to the neurologic side effects of psychotropic medications. This increased sensitivity may be related to brain structural changes associated with aging. In this pilot study, the authors report on the occurrence of caudate hyperintensities, using brain magnetic resonance imaging, in seven elderly depressed subjects who developed neuroleptic-induced parkinsonism. Caudate hyperintensities were not observed in any of the seven healthy elderly controls examined. These results suggest that caudate hyperintensities may render some elderly depressed patients susceptible to neuroleptic-induced parkinsonism.

Duke Scholars

Published In

J Geriatr Psychiatry Neurol

DOI

ISSN

0891-9887

Publication Date

1991

Volume

4

Issue

2

Start / End Page

86 / 89

Location

United States

Related Subject Headings

  • Pilot Projects
  • Parkinson Disease, Secondary
  • Middle Aged
  • Male
  • Magnetic Resonance Imaging
  • Humans
  • Geriatrics
  • Female
  • Depression
  • Caudate Nucleus
 

Citation

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ICMJE
MLA
NLM
Figiel, G. S., Krishnan, K. R., Doraiswamy, P. M., & Nemeroff, C. B. (1991). Caudate hyperintensities in elderly depressed patients with neuroleptic-induced parkinsonism. J Geriatr Psychiatry Neurol, 4(2), 86–89. https://doi.org/10.1177/089198879100400206
Figiel, G. S., K. R. Krishnan, P. M. Doraiswamy, and C. B. Nemeroff. “Caudate hyperintensities in elderly depressed patients with neuroleptic-induced parkinsonism.J Geriatr Psychiatry Neurol 4, no. 2 (1991): 86–89. https://doi.org/10.1177/089198879100400206.
Figiel GS, Krishnan KR, Doraiswamy PM, Nemeroff CB. Caudate hyperintensities in elderly depressed patients with neuroleptic-induced parkinsonism. J Geriatr Psychiatry Neurol. 1991;4(2):86–9.
Figiel, G. S., et al. “Caudate hyperintensities in elderly depressed patients with neuroleptic-induced parkinsonism.J Geriatr Psychiatry Neurol, vol. 4, no. 2, 1991, pp. 86–89. Pubmed, doi:10.1177/089198879100400206.
Figiel GS, Krishnan KR, Doraiswamy PM, Nemeroff CB. Caudate hyperintensities in elderly depressed patients with neuroleptic-induced parkinsonism. J Geriatr Psychiatry Neurol. 1991;4(2):86–89.
Journal cover image

Published In

J Geriatr Psychiatry Neurol

DOI

ISSN

0891-9887

Publication Date

1991

Volume

4

Issue

2

Start / End Page

86 / 89

Location

United States

Related Subject Headings

  • Pilot Projects
  • Parkinson Disease, Secondary
  • Middle Aged
  • Male
  • Magnetic Resonance Imaging
  • Humans
  • Geriatrics
  • Female
  • Depression
  • Caudate Nucleus