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In vivo assessment of pituitary gland volume with magnetic resonance imaging: the effect of age.

Publication ,  Journal Article
Lurie, SN; Doraiswamy, PM; Husain, MM; Boyko, OB; Ellinwood, EH; Figiel, GS; Krishnan, KR
Published in: J Clin Endocrinol Metab
August 1990

We used sagittal and coronal T1 weighted magnetic resonance images, at 1.5 Tesla, to measure the height, width, length, and cross-sectional area and to generate two estimates of pituitary gland volume in 35 normal volunteers aged 26-79 yr (19 females and 16 males). Subjects over 50 yr of age had significantly smaller pituitary gland height (P = 0.03), area (P = 0.04), and volume (P = 0.04) than those under 50 yr (by two-tailed t test). Overall, age was negatively correlated with pituitary volume (V1: r = -0.51; P = 0.003; V2: r = -0.47; P = 0.008), area (r = -0.43; P = 0.009), and height (r = -0.46; P = 0.005), but not with pituitary length or width. There were no statistically significant differences in pituitary size between men and women (by two-tailed t test). These findings suggest that pituitary gland height provides a good single measure for the assessment of pituitary gland size and that age must be controlled for in studies of pituitary gland size.

Duke Scholars

Published In

J Clin Endocrinol Metab

DOI

ISSN

0021-972X

Publication Date

August 1990

Volume

71

Issue

2

Start / End Page

505 / 508

Location

United States

Related Subject Headings

  • Sex Factors
  • Reference Values
  • Pituitary Gland
  • Middle Aged
  • Male
  • Magnetic Resonance Imaging
  • Humans
  • Female
  • Endocrinology & Metabolism
  • Aging
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Lurie, S. N., Doraiswamy, P. M., Husain, M. M., Boyko, O. B., Ellinwood, E. H., Figiel, G. S., & Krishnan, K. R. (1990). In vivo assessment of pituitary gland volume with magnetic resonance imaging: the effect of age. J Clin Endocrinol Metab, 71(2), 505–508. https://doi.org/10.1210/jcem-71-2-505
Lurie, S. N., P. M. Doraiswamy, M. M. Husain, O. B. Boyko, E. H. Ellinwood, G. S. Figiel, and K. R. Krishnan. “In vivo assessment of pituitary gland volume with magnetic resonance imaging: the effect of age.J Clin Endocrinol Metab 71, no. 2 (August 1990): 505–8. https://doi.org/10.1210/jcem-71-2-505.
Lurie SN, Doraiswamy PM, Husain MM, Boyko OB, Ellinwood EH, Figiel GS, et al. In vivo assessment of pituitary gland volume with magnetic resonance imaging: the effect of age. J Clin Endocrinol Metab. 1990 Aug;71(2):505–8.
Lurie, S. N., et al. “In vivo assessment of pituitary gland volume with magnetic resonance imaging: the effect of age.J Clin Endocrinol Metab, vol. 71, no. 2, Aug. 1990, pp. 505–08. Pubmed, doi:10.1210/jcem-71-2-505.
Lurie SN, Doraiswamy PM, Husain MM, Boyko OB, Ellinwood EH, Figiel GS, Krishnan KR. In vivo assessment of pituitary gland volume with magnetic resonance imaging: the effect of age. J Clin Endocrinol Metab. 1990 Aug;71(2):505–508.
Journal cover image

Published In

J Clin Endocrinol Metab

DOI

ISSN

0021-972X

Publication Date

August 1990

Volume

71

Issue

2

Start / End Page

505 / 508

Location

United States

Related Subject Headings

  • Sex Factors
  • Reference Values
  • Pituitary Gland
  • Middle Aged
  • Male
  • Magnetic Resonance Imaging
  • Humans
  • Female
  • Endocrinology & Metabolism
  • Aging