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Differential expression of genes encoding TGFs beta 1, beta 2, and beta 3 during murine palate formation.

Publication ,  Journal Article
Pelton, RW; Hogan, BL; Miller, DA; Moses, HL
Published in: Dev Biol
October 1990

Transforming growth factor beta 1 (TGF beta 1) has been shown to have multiple effects on primary cultures of palate-derived cell types. We report the analysis, by in situ hybridization, of RNA expression for three different TGF beta isoforms (TGF beta 1, beta 2, and beta 3) during murine embryonic palate development. Differential expression of the three TGF beta genes is seen in the palatal shelves in mesenchymal and epithelial cells known to be involved in the morphogenesis of this organ. Taken together, these results suggest that the TGF beta s act as endogenous factors involved in the formation of the mammalian palate.

Duke Scholars

Published In

Dev Biol

DOI

ISSN

0012-1606

Publication Date

October 1990

Volume

141

Issue

2

Start / End Page

456 / 460

Location

United States

Related Subject Headings

  • Transforming Growth Factor beta
  • RNA
  • Pregnancy
  • Palate
  • Nucleic Acid Hybridization
  • Mice, Inbred ICR
  • Mice
  • Male
  • Gene Expression Regulation
  • Female
 

Citation

APA
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ICMJE
MLA
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Pelton, R. W., Hogan, B. L., Miller, D. A., & Moses, H. L. (1990). Differential expression of genes encoding TGFs beta 1, beta 2, and beta 3 during murine palate formation. Dev Biol, 141(2), 456–460. https://doi.org/10.1016/0012-1606(90)90401-4
Pelton, R. W., B. L. Hogan, D. A. Miller, and H. L. Moses. “Differential expression of genes encoding TGFs beta 1, beta 2, and beta 3 during murine palate formation.Dev Biol 141, no. 2 (October 1990): 456–60. https://doi.org/10.1016/0012-1606(90)90401-4.
Pelton RW, Hogan BL, Miller DA, Moses HL. Differential expression of genes encoding TGFs beta 1, beta 2, and beta 3 during murine palate formation. Dev Biol. 1990 Oct;141(2):456–60.
Pelton, R. W., et al. “Differential expression of genes encoding TGFs beta 1, beta 2, and beta 3 during murine palate formation.Dev Biol, vol. 141, no. 2, Oct. 1990, pp. 456–60. Pubmed, doi:10.1016/0012-1606(90)90401-4.
Pelton RW, Hogan BL, Miller DA, Moses HL. Differential expression of genes encoding TGFs beta 1, beta 2, and beta 3 during murine palate formation. Dev Biol. 1990 Oct;141(2):456–460.
Journal cover image

Published In

Dev Biol

DOI

ISSN

0012-1606

Publication Date

October 1990

Volume

141

Issue

2

Start / End Page

456 / 460

Location

United States

Related Subject Headings

  • Transforming Growth Factor beta
  • RNA
  • Pregnancy
  • Palate
  • Nucleic Acid Hybridization
  • Mice, Inbred ICR
  • Mice
  • Male
  • Gene Expression Regulation
  • Female