The energetics of binding of a signal peptide to lipid bilayers: the role of bilayer properties.
Publication
, Journal Article
McIntosh, TJ; Vidal, A; Simon, SA
Published in: Biochem Soc Trans
August 2001
The interactions between a signal peptide and a variety of lipid bilayers have been studied with direct binding assays, CD and isothermal titration calorimetry. We find that the binding of this peptide is influenced by charges and dipoles located in the bilayer interfacial region, as well as by the presence of cholesterol in the bilayer. These studies show that bilayer compositional and mechanical variations found in different biological membranes can affect the partitioning of peptides into the bilayer.
Duke Scholars
Published In
Biochem Soc Trans
DOI
ISSN
0300-5127
Publication Date
August 2001
Volume
29
Issue
Pt 4
Start / End Page
594 / 598
Location
England
Related Subject Headings
- Thermodynamics
- Protein Sorting Signals
- Peptides
- Molecular Sequence Data
- Lipid Bilayers
- Biochemistry & Molecular Biology
- Binding Sites
- Amino Acid Sequence
- 3101 Biochemistry and cell biology
- 1101 Medical Biochemistry and Metabolomics
Citation
APA
Chicago
ICMJE
MLA
NLM
McIntosh, T. J., Vidal, A., & Simon, S. A. (2001). The energetics of binding of a signal peptide to lipid bilayers: the role of bilayer properties. Biochem Soc Trans, 29(Pt 4), 594–598. https://doi.org/10.1042/bst0290594
McIntosh, T. J., A. Vidal, and S. A. Simon. “The energetics of binding of a signal peptide to lipid bilayers: the role of bilayer properties.” Biochem Soc Trans 29, no. Pt 4 (August 2001): 594–98. https://doi.org/10.1042/bst0290594.
McIntosh TJ, Vidal A, Simon SA. The energetics of binding of a signal peptide to lipid bilayers: the role of bilayer properties. Biochem Soc Trans. 2001 Aug;29(Pt 4):594–8.
McIntosh, T. J., et al. “The energetics of binding of a signal peptide to lipid bilayers: the role of bilayer properties.” Biochem Soc Trans, vol. 29, no. Pt 4, Aug. 2001, pp. 594–98. Pubmed, doi:10.1042/bst0290594.
McIntosh TJ, Vidal A, Simon SA. The energetics of binding of a signal peptide to lipid bilayers: the role of bilayer properties. Biochem Soc Trans. 2001 Aug;29(Pt 4):594–598.
Published In
Biochem Soc Trans
DOI
ISSN
0300-5127
Publication Date
August 2001
Volume
29
Issue
Pt 4
Start / End Page
594 / 598
Location
England
Related Subject Headings
- Thermodynamics
- Protein Sorting Signals
- Peptides
- Molecular Sequence Data
- Lipid Bilayers
- Biochemistry & Molecular Biology
- Binding Sites
- Amino Acid Sequence
- 3101 Biochemistry and cell biology
- 1101 Medical Biochemistry and Metabolomics