Handedness of crossover connections in beta sheets.
Publication
, Journal Article
Richardson, JS
Published in: Proc Natl Acad Sci U S A
August 1976
In a crossover connection, the polypeptide chain leaves one end of a beta sheet, forms a loop of any length and any conformation, and reenters the same beta sheet from the opposite end. Of the 85 examples of crossover connections which occur in the known protein structures, 83 are righthanded and only two are lefthanded. It is proposed that consistent handedness, even in long irregular loops, could be produced by the preferred twist direction of extended chain and the righthandedness of alpha-helices, provided certain conditions hold during the protein folding process.
Duke Scholars
Published In
Proc Natl Acad Sci U S A
DOI
ISSN
0027-8424
Publication Date
August 1976
Volume
73
Issue
8
Start / End Page
2619 / 2623
Location
United States
Related Subject Headings
- Subtilisins
- Protein Conformation
- Phosphoglycerate Mutase
- Phosphoglycerate Kinase
- Models, Structural
- Hexokinase
- Glyceraldehyde-3-Phosphate Dehydrogenases
- Carboxypeptidases
Citation
APA
Chicago
ICMJE
MLA
NLM
Richardson, J. S. (1976). Handedness of crossover connections in beta sheets. Proc Natl Acad Sci U S A, 73(8), 2619–2623. https://doi.org/10.1073/pnas.73.8.2619
Richardson, J. S. “Handedness of crossover connections in beta sheets.” Proc Natl Acad Sci U S A 73, no. 8 (August 1976): 2619–23. https://doi.org/10.1073/pnas.73.8.2619.
Richardson JS. Handedness of crossover connections in beta sheets. Proc Natl Acad Sci U S A. 1976 Aug;73(8):2619–23.
Richardson, J. S. “Handedness of crossover connections in beta sheets.” Proc Natl Acad Sci U S A, vol. 73, no. 8, Aug. 1976, pp. 2619–23. Pubmed, doi:10.1073/pnas.73.8.2619.
Richardson JS. Handedness of crossover connections in beta sheets. Proc Natl Acad Sci U S A. 1976 Aug;73(8):2619–2623.
Published In
Proc Natl Acad Sci U S A
DOI
ISSN
0027-8424
Publication Date
August 1976
Volume
73
Issue
8
Start / End Page
2619 / 2623
Location
United States
Related Subject Headings
- Subtilisins
- Protein Conformation
- Phosphoglycerate Mutase
- Phosphoglycerate Kinase
- Models, Structural
- Hexokinase
- Glyceraldehyde-3-Phosphate Dehydrogenases
- Carboxypeptidases