Skip to main content
Journal cover image

Cerebellar activity and disturbed time sense after THC.

Publication ,  Journal Article
Mathew, RJ; Wilson, WH; Turkington, TG; Coleman, RE
Published in: Brain Res
June 29, 1998

Because marijuana continues to be the most commonly used illicit drug, its effects on the brain function are of major interest. We utilized positron emission tomography (PET) and magnetic resonance imaging (MRI) to study the effects of delta-9-tetrahydrocannabinol (THC) infusion on brain blood flow and its behavioral correlates in 46 volunteers. Consistent with previous reports, there was a significant increase in cortical and cerebellar blood flow following THC, but not all subjects showed this effect. Those who showed a decrease in cerebellar CBF also had a significant alteration in time sense. The relationship between decreased cerebellar flow and impaired time sense is of interest because the cerebellum has been linked to an internal timing system.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

Brain Res

DOI

ISSN

0006-8993

Publication Date

June 29, 1998

Volume

797

Issue

2

Start / End Page

183 / 189

Location

Netherlands

Related Subject Headings

  • Tomography, Emission-Computed
  • Time Perception
  • Regression Analysis
  • Neurology & Neurosurgery
  • Male
  • Magnetic Resonance Imaging
  • Humans
  • Hallucinogens
  • Gyrus Cinguli
  • Female
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Mathew, R. J., Wilson, W. H., Turkington, T. G., & Coleman, R. E. (1998). Cerebellar activity and disturbed time sense after THC. Brain Res, 797(2), 183–189. https://doi.org/10.1016/s0006-8993(98)00375-8
Mathew, R. J., W. H. Wilson, T. G. Turkington, and R. E. Coleman. “Cerebellar activity and disturbed time sense after THC.Brain Res 797, no. 2 (June 29, 1998): 183–89. https://doi.org/10.1016/s0006-8993(98)00375-8.
Mathew RJ, Wilson WH, Turkington TG, Coleman RE. Cerebellar activity and disturbed time sense after THC. Brain Res. 1998 Jun 29;797(2):183–9.
Mathew, R. J., et al. “Cerebellar activity and disturbed time sense after THC.Brain Res, vol. 797, no. 2, June 1998, pp. 183–89. Pubmed, doi:10.1016/s0006-8993(98)00375-8.
Mathew RJ, Wilson WH, Turkington TG, Coleman RE. Cerebellar activity and disturbed time sense after THC. Brain Res. 1998 Jun 29;797(2):183–189.
Journal cover image

Published In

Brain Res

DOI

ISSN

0006-8993

Publication Date

June 29, 1998

Volume

797

Issue

2

Start / End Page

183 / 189

Location

Netherlands

Related Subject Headings

  • Tomography, Emission-Computed
  • Time Perception
  • Regression Analysis
  • Neurology & Neurosurgery
  • Male
  • Magnetic Resonance Imaging
  • Humans
  • Hallucinogens
  • Gyrus Cinguli
  • Female