Transgenic animals in integrative biology: approaches and interpretations of outcome.
Publication
, Journal Article
Williams, RS; Wagner, PD
Published in: J Appl Physiol (1985)
March 2000
Technological innovations in methods for genetic manipulation of laboratory animals and in techniques for assessment of cardiovascular, respiratory, behavioral, and metabolic physiology in mouse models afford unprecedented opportunities for research in integrative biology. We provide here an overview of basic and advanced techniques for generation of transgenic mice and a discussion of how transgenic technology can be most advantageously applied to important physiological questions that can be addressed only within the intact organism.
Duke Scholars
Altmetric Attention Stats
Dimensions Citation Stats
Published In
J Appl Physiol (1985)
DOI
ISSN
8750-7587
Publication Date
March 2000
Volume
88
Issue
3
Start / End Page
1119 / 1126
Location
United States
Related Subject Headings
- Physiology
- Mice, Transgenic
- Mice, Knockout
- Mice
- Male
- Genetic Techniques
- Female
- Disease Models, Animal
- Animals, Genetically Modified
- Animals
Citation
APA
Chicago
ICMJE
MLA
NLM
Williams, R. S., & Wagner, P. D. (2000). Transgenic animals in integrative biology: approaches and interpretations of outcome. J Appl Physiol (1985), 88(3), 1119–1126. https://doi.org/10.1152/jappl.2000.88.3.1119
Williams, R. S., and P. D. Wagner. “Transgenic animals in integrative biology: approaches and interpretations of outcome.” J Appl Physiol (1985) 88, no. 3 (March 2000): 1119–26. https://doi.org/10.1152/jappl.2000.88.3.1119.
Williams RS, Wagner PD. Transgenic animals in integrative biology: approaches and interpretations of outcome. J Appl Physiol (1985). 2000 Mar;88(3):1119–26.
Williams, R. S., and P. D. Wagner. “Transgenic animals in integrative biology: approaches and interpretations of outcome.” J Appl Physiol (1985), vol. 88, no. 3, Mar. 2000, pp. 1119–26. Pubmed, doi:10.1152/jappl.2000.88.3.1119.
Williams RS, Wagner PD. Transgenic animals in integrative biology: approaches and interpretations of outcome. J Appl Physiol (1985). 2000 Mar;88(3):1119–1126.
Published In
J Appl Physiol (1985)
DOI
ISSN
8750-7587
Publication Date
March 2000
Volume
88
Issue
3
Start / End Page
1119 / 1126
Location
United States
Related Subject Headings
- Physiology
- Mice, Transgenic
- Mice, Knockout
- Mice
- Male
- Genetic Techniques
- Female
- Disease Models, Animal
- Animals, Genetically Modified
- Animals