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The development of new biotechnologies using metalloprotein design.

Publication ,  Journal Article
Benson, DE; Wisz, MS; Hellinga, HW
Published in: Curr Opin Biotechnol
August 1998

A variety of methodologies are under development to alter the behavior of existing metal centers or create entirely new sites within a protein framework in order to exploit the intrinsic chemical versatility of metals using the exquisite level of control that a protein matrix can exert to modulate their reactivity. Even at this relatively early stage, engineering of metal centers has led to the development of a number of emerging technologies with a wide variety of applications, including affinity purification of proteins, engineering of metal-mediated protein stability, control of protein activity, imaging and therapy, biosensors, and new catalysts.

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Published In

Curr Opin Biotechnol

DOI

EISSN

1879-0429

Publication Date

August 1998

Volume

9

Issue

4

Start / End Page

370 / 376

Location

England

Related Subject Headings

  • Biotechnology
  • 3206 Medical biotechnology
  • 3106 Industrial biotechnology
  • 3001 Agricultural biotechnology
  • 10 Technology
  • 09 Engineering
  • 06 Biological Sciences
 

Citation

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ICMJE
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Benson, D. E., Wisz, M. S., & Hellinga, H. W. (1998). The development of new biotechnologies using metalloprotein design. Curr Opin Biotechnol, 9(4), 370–376. https://doi.org/10.1016/s0958-1669(98)80010-4
Benson, D. E., M. S. Wisz, and H. W. Hellinga. “The development of new biotechnologies using metalloprotein design.Curr Opin Biotechnol 9, no. 4 (August 1998): 370–76. https://doi.org/10.1016/s0958-1669(98)80010-4.
Benson DE, Wisz MS, Hellinga HW. The development of new biotechnologies using metalloprotein design. Curr Opin Biotechnol. 1998 Aug;9(4):370–6.
Benson, D. E., et al. “The development of new biotechnologies using metalloprotein design.Curr Opin Biotechnol, vol. 9, no. 4, Aug. 1998, pp. 370–76. Pubmed, doi:10.1016/s0958-1669(98)80010-4.
Benson DE, Wisz MS, Hellinga HW. The development of new biotechnologies using metalloprotein design. Curr Opin Biotechnol. 1998 Aug;9(4):370–376.
Journal cover image

Published In

Curr Opin Biotechnol

DOI

EISSN

1879-0429

Publication Date

August 1998

Volume

9

Issue

4

Start / End Page

370 / 376

Location

England

Related Subject Headings

  • Biotechnology
  • 3206 Medical biotechnology
  • 3106 Industrial biotechnology
  • 3001 Agricultural biotechnology
  • 10 Technology
  • 09 Engineering
  • 06 Biological Sciences