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Studies of viral antibody responses among Amish families.

Publication ,  Journal Article
Hsia, S; Howell, DN; Amos, DB; Woodbury, MA
Published in: J Immunol
May 1977

Serum antibodies to adenovirus (ADN), cytomegalovirus (CMV), herpes simplex virus (HSV), influenza (INF), para-influenza (PAR), mumps (MUM), coxsackie B4 (Cox B4) and B5 (Cox B5) viruses were measured from 584 individuals belonging to 21 Indiana Amish families. Sex and age effects on antibody responses to cytomegalovirus were observed. Age effect on CMV, HSV, INF, PAR, MUM responses were also found. The percentage of responders to some of the viruses was shown to be age dependent, but the levels of antibody response were not affected by the difference in age. A familial basis for the antibody response was demonstrated. Attempts at demonstrating association between HLA haplotypes and responses were not successful. The unlikelihood of predominantly HLA-associated control of viral antibody response was discussed.

Duke Scholars

Published In

J Immunol

ISSN

0022-1767

Publication Date

May 1977

Volume

118

Issue

5

Start / End Page

1659 / 1664

Location

United States

Related Subject Headings

  • Simplexvirus
  • Sex Factors
  • Respirovirus
  • Orthomyxoviridae
  • Mumps virus
  • Middle Aged
  • Male
  • Indiana
  • Immunology
  • Humans
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Hsia, S., Howell, D. N., Amos, D. B., & Woodbury, M. A. (1977). Studies of viral antibody responses among Amish families. J Immunol, 118(5), 1659–1664.
Hsia, S., D. N. Howell, D. B. Amos, and M. A. Woodbury. “Studies of viral antibody responses among Amish families.J Immunol 118, no. 5 (May 1977): 1659–64.
Hsia S, Howell DN, Amos DB, Woodbury MA. Studies of viral antibody responses among Amish families. J Immunol. 1977 May;118(5):1659–64.
Hsia, S., et al. “Studies of viral antibody responses among Amish families.J Immunol, vol. 118, no. 5, May 1977, pp. 1659–64.
Hsia S, Howell DN, Amos DB, Woodbury MA. Studies of viral antibody responses among Amish families. J Immunol. 1977 May;118(5):1659–1664.

Published In

J Immunol

ISSN

0022-1767

Publication Date

May 1977

Volume

118

Issue

5

Start / End Page

1659 / 1664

Location

United States

Related Subject Headings

  • Simplexvirus
  • Sex Factors
  • Respirovirus
  • Orthomyxoviridae
  • Mumps virus
  • Middle Aged
  • Male
  • Indiana
  • Immunology
  • Humans