Inability of encapsulated Klebsiella pneumoniae to assemble functional type 1 fimbriae on their surface.
Publication
, Journal Article
Matatov, R; Goldhar, J; Skutelsky, E; Sechter, I; Perry, R; Podschun, R; Sahly, H; Thankavel, K; Abraham, SN; Ofek, I
Published in: FEMS Microbiol Lett
October 1, 1999
We screened phase variants of Klebsiella pneumoniae isolates for the expression of capsule and type 1 fimbriae and found that all of the 22 blood isolates were encapsulated and did not express type 1 fimbriae while 10 of 11 urinary tract isolates expressed type 1 fimbriae but were unencapsulated. Phase variants from selected isolates were found to be either unencapsulated and fimbriated or lacked both structures. Variants expressing both structures were not detected. Fimbrial subunits FimH and FimA were localized in the periplasmic space of the parent strain and on the surface of the unencapsulated variants. The results suggest that capsule formation impedes assembly of pre-formed fimbrial subunits on the bacterial surface.
Duke Scholars
Published In
FEMS Microbiol Lett
DOI
ISSN
0378-1097
Publication Date
October 1, 1999
Volume
179
Issue
1
Start / End Page
123 / 130
Location
England
Related Subject Headings
- Urinary Tract Infections
- Serotyping
- Microscopy, Immunoelectron
- Microbiology
- Klebsiella pneumoniae
- Klebsiella Infections
- Humans
- Fimbriae, Bacterial
- Bacteremia
- 32 Biomedical and clinical sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Matatov, R., Goldhar, J., Skutelsky, E., Sechter, I., Perry, R., Podschun, R., … Ofek, I. (1999). Inability of encapsulated Klebsiella pneumoniae to assemble functional type 1 fimbriae on their surface. FEMS Microbiol Lett, 179(1), 123–130. https://doi.org/10.1111/j.1574-6968.1999.tb08717.x
Matatov, R., J. Goldhar, E. Skutelsky, I. Sechter, R. Perry, R. Podschun, H. Sahly, K. Thankavel, S. N. Abraham, and I. Ofek. “Inability of encapsulated Klebsiella pneumoniae to assemble functional type 1 fimbriae on their surface.” FEMS Microbiol Lett 179, no. 1 (October 1, 1999): 123–30. https://doi.org/10.1111/j.1574-6968.1999.tb08717.x.
Matatov R, Goldhar J, Skutelsky E, Sechter I, Perry R, Podschun R, et al. Inability of encapsulated Klebsiella pneumoniae to assemble functional type 1 fimbriae on their surface. FEMS Microbiol Lett. 1999 Oct 1;179(1):123–30.
Matatov, R., et al. “Inability of encapsulated Klebsiella pneumoniae to assemble functional type 1 fimbriae on their surface.” FEMS Microbiol Lett, vol. 179, no. 1, Oct. 1999, pp. 123–30. Pubmed, doi:10.1111/j.1574-6968.1999.tb08717.x.
Matatov R, Goldhar J, Skutelsky E, Sechter I, Perry R, Podschun R, Sahly H, Thankavel K, Abraham SN, Ofek I. Inability of encapsulated Klebsiella pneumoniae to assemble functional type 1 fimbriae on their surface. FEMS Microbiol Lett. 1999 Oct 1;179(1):123–130.
Published In
FEMS Microbiol Lett
DOI
ISSN
0378-1097
Publication Date
October 1, 1999
Volume
179
Issue
1
Start / End Page
123 / 130
Location
England
Related Subject Headings
- Urinary Tract Infections
- Serotyping
- Microscopy, Immunoelectron
- Microbiology
- Klebsiella pneumoniae
- Klebsiella Infections
- Humans
- Fimbriae, Bacterial
- Bacteremia
- 32 Biomedical and clinical sciences