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NPR1 modulates cross-talk between salicylate- and jasmonate-dependent defense pathways through a novel function in the cytosol.

Publication ,  Journal Article
Spoel, SH; Koornneef, A; Claessens, SMC; Korzelius, JP; Van Pelt, JA; Mueller, MJ; Buchala, AJ; Métraux, J-P; Brown, R; Kazan, K; Van Loon, LC ...
Published in: The Plant cell
March 2003

Plant defenses against pathogens and insects are regulated differentially by cross-communicating signal transduction pathways in which salicylic acid (SA) and jasmonic acid (JA) play key roles. In this study, we investigated the molecular mechanism of the antagonistic effect of SA on JA signaling. Arabidopsis plants unable to accumulate SA produced 25-fold higher levels of JA and showed enhanced expression of the JA-responsive genes LOX2, PDF1.2, and VSP in response to infection by Pseudomonas syringae pv tomato DC3000, indicating that in wild-type plants, pathogen-induced SA accumulation is associated with the suppression of JA signaling. Analysis of the Arabidopsis mutant npr1, which is impaired in SA signal transduction, revealed that the antagonistic effect of SA on JA signaling requires the regulatory protein NPR1. Nuclear localization of NPR1, which is essential for SA-mediated defense gene expression, is not required for the suppression of JA signaling, indicating that cross-talk between SA and JA is modulated through a novel function of NPR1 in the cytosol.

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Published In

The Plant cell

DOI

EISSN

1532-298X

ISSN

1040-4651

Publication Date

March 2003

Volume

15

Issue

3

Start / End Page

760 / 770

Related Subject Headings

  • Transcription Factors
  • Signal Transduction
  • Salicylic Acid
  • Pseudomonas
  • Plant Proteins
  • Plant Diseases
  • Plant Biology & Botany
  • Oxylipins
  • Nuclear Proteins
  • Molecular Sequence Data
 

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Spoel, S. H., Koornneef, A., Claessens, S. M. C., Korzelius, J. P., Van Pelt, J. A., Mueller, M. J., … Pieterse, C. M. J. (2003). NPR1 modulates cross-talk between salicylate- and jasmonate-dependent defense pathways through a novel function in the cytosol. The Plant Cell, 15(3), 760–770. https://doi.org/10.1105/tpc.009159
Spoel, Steven H., Annemart Koornneef, Susanne M. C. Claessens, Jerôme P. Korzelius, Johan A. Van Pelt, Martin J. Mueller, Antony J. Buchala, et al. “NPR1 modulates cross-talk between salicylate- and jasmonate-dependent defense pathways through a novel function in the cytosol.The Plant Cell 15, no. 3 (March 2003): 760–70. https://doi.org/10.1105/tpc.009159.
Spoel SH, Koornneef A, Claessens SMC, Korzelius JP, Van Pelt JA, Mueller MJ, et al. NPR1 modulates cross-talk between salicylate- and jasmonate-dependent defense pathways through a novel function in the cytosol. The Plant cell. 2003 Mar;15(3):760–70.
Spoel, Steven H., et al. “NPR1 modulates cross-talk between salicylate- and jasmonate-dependent defense pathways through a novel function in the cytosol.The Plant Cell, vol. 15, no. 3, Mar. 2003, pp. 760–70. Epmc, doi:10.1105/tpc.009159.
Spoel SH, Koornneef A, Claessens SMC, Korzelius JP, Van Pelt JA, Mueller MJ, Buchala AJ, Métraux J-P, Brown R, Kazan K, Van Loon LC, Dong X, Pieterse CMJ. NPR1 modulates cross-talk between salicylate- and jasmonate-dependent defense pathways through a novel function in the cytosol. The Plant cell. 2003 Mar;15(3):760–770.

Published In

The Plant cell

DOI

EISSN

1532-298X

ISSN

1040-4651

Publication Date

March 2003

Volume

15

Issue

3

Start / End Page

760 / 770

Related Subject Headings

  • Transcription Factors
  • Signal Transduction
  • Salicylic Acid
  • Pseudomonas
  • Plant Proteins
  • Plant Diseases
  • Plant Biology & Botany
  • Oxylipins
  • Nuclear Proteins
  • Molecular Sequence Data