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Osteogenic sarcoma of the head and neck. The UCLA experience.

Publication ,  Journal Article
Mark, RJ; Sercarz, JA; Tran, L; Dodd, LG; Selch, M; Calcaterra, TC
Published in: Arch Otolaryngol Head Neck Surg
July 1991

Eighteen cases of osteogenic sarcoma of the head and neck were treated at our institution between 1955 and 1987. The patients' ages ranged from 5 to 73 years, with a median age of 28 years. The sex distribution was equal. Follow-up ranged from 1 to 276 months, with a median of 79 months. The primary site of the tumor was the mandible in nine cases, maxilla and paranasal sinuses in six, skull in two, and orbit in one. Six of 18 patients were free of disease with greater than 5 years of follow-up. Four of the six received combined surgery, radiation therapy, and chemotherapy as their primary treatment. Of the five patients treated with surgery alone, four suffered recurrences, one of whom was salvaged with further surgery and chemotherapy. Five patients were treated initially without surgery. They received radiation therapy with or without chemotherapy; all five developed local recurrence. We conclude that osteogenic sarcoma of the head and neck is an aggressive tumor, prone to both local and distant failure. Based on our series and from published experience involving the extremities, osteogenic sarcoma of the head and neck should be managed with multimodality therapy.

Duke Scholars

Published In

Arch Otolaryngol Head Neck Surg

DOI

ISSN

0886-4470

Publication Date

July 1991

Volume

117

Issue

7

Start / End Page

761 / 766

Location

United States

Related Subject Headings

  • Survival Rate
  • Retrospective Studies
  • Otorhinolaryngology
  • Osteosarcoma
  • Neoplasm Staging
  • Neoplasm Recurrence, Local
  • Middle Aged
  • Male
  • Lymphatic Metastasis
  • Lung Neoplasms
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Mark, R. J., Sercarz, J. A., Tran, L., Dodd, L. G., Selch, M., & Calcaterra, T. C. (1991). Osteogenic sarcoma of the head and neck. The UCLA experience. Arch Otolaryngol Head Neck Surg, 117(7), 761–766. https://doi.org/10.1001/archotol.1991.01870190073015
Mark, R. J., J. A. Sercarz, L. Tran, L. G. Dodd, M. Selch, and T. C. Calcaterra. “Osteogenic sarcoma of the head and neck. The UCLA experience.Arch Otolaryngol Head Neck Surg 117, no. 7 (July 1991): 761–66. https://doi.org/10.1001/archotol.1991.01870190073015.
Mark RJ, Sercarz JA, Tran L, Dodd LG, Selch M, Calcaterra TC. Osteogenic sarcoma of the head and neck. The UCLA experience. Arch Otolaryngol Head Neck Surg. 1991 Jul;117(7):761–6.
Mark, R. J., et al. “Osteogenic sarcoma of the head and neck. The UCLA experience.Arch Otolaryngol Head Neck Surg, vol. 117, no. 7, July 1991, pp. 761–66. Pubmed, doi:10.1001/archotol.1991.01870190073015.
Mark RJ, Sercarz JA, Tran L, Dodd LG, Selch M, Calcaterra TC. Osteogenic sarcoma of the head and neck. The UCLA experience. Arch Otolaryngol Head Neck Surg. 1991 Jul;117(7):761–766.

Published In

Arch Otolaryngol Head Neck Surg

DOI

ISSN

0886-4470

Publication Date

July 1991

Volume

117

Issue

7

Start / End Page

761 / 766

Location

United States

Related Subject Headings

  • Survival Rate
  • Retrospective Studies
  • Otorhinolaryngology
  • Osteosarcoma
  • Neoplasm Staging
  • Neoplasm Recurrence, Local
  • Middle Aged
  • Male
  • Lymphatic Metastasis
  • Lung Neoplasms