Fine-needle aspiration cytology of silicone granulomas in the augmented breast.
We studied 12 aspirates from 10 patients who underwent diagnostic fine-needle aspiration cytology (FNAC) of an augmented or reconstructed breast. Six patients were augmented with silicone gel-filled implants and four patients had silicone liquid injections. FNAC indications included a painful or suspicious mass. Excisional biopsy was performed in six cases after FNAC. The findings of eight cases included modestly cellular smears composed of loosely cohesive histiocytes containing vacuoles of various sizes. Multinucleated foreign body giant cells, fragments of dense, amorphous fibrous tissue, and fibroblast nuclei stripped of cytoplasm were also present. Two patients showed a mixture of inflammatory cells characteristic of intramammary lymph nodes or lymphoid aggregates. We conclude that silicone granulomas of the breast show a characteristic set of findings on FNAC which enable a cytopathologist to render a specific diagnosis given an appropriate history of breast augmentation.
Duke Scholars
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- Silicones
- Prostheses and Implants
- Pathology
- Middle Aged
- Mammaplasty
- Humans
- Granuloma
- Female
- Breast Diseases
- Biopsy, Needle
Citation
Published In
DOI
ISSN
Publication Date
Volume
Issue
Start / End Page
Location
Related Subject Headings
- Silicones
- Prostheses and Implants
- Pathology
- Middle Aged
- Mammaplasty
- Humans
- Granuloma
- Female
- Breast Diseases
- Biopsy, Needle