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Institutional review of outside cytology materials: a retrospective analysis of two institutions' experiences.

Publication ,  Journal Article
Layfield, LJ; Jones, C; Rowe, L; Gopez, EV
Published in: Diagn Cytopathol
January 2002

Discrepancy rates between original and review histopathologic diagnoses have been well-studied, and range as high as 30% in some studies. While the sensitivity and specificity rates for a variety of cytologic specimens are well-known, few data exist as to the discrepancy rates associated with in-house, second-opinion reviews of outside material. We studied the 2-yr experience of two university-based medical centers' reviews of outside cytology materials. A total of 146 cases underwent second-opinion review. The majority were fine-needle aspiration specimens obtained from the breast, thyroid, lung, and hematobiliary system. Nine cases were cervical vaginal specimens, 19 were bronchial brushes, washings, or lavage specimens, 13 were pleural fluid specimens, 5 were bile duct brushings, and the remainder were exfoliative cytologies, including those from the cerebrospinal fluid, urine, and pelvis. In all, 24 disagreements were encountered, 11 of which were considered major in that a significant change in therapy occurred due to an alteration in diagnosis, while 13 were considered minor in that a different diagnosis or subclassification was given by the consultant pathologist, but this diagnostic change did not significantly alter therapy. The overall diagnosis disagreement rate of 16% is similar to the diagnostic discrepancy rate encountered in second-opinion reviews of surgical pathology specimens. The 8% major discrepancy rate is slightly higher than that seen in similar studies of surgical pathology material.

Duke Scholars

Published In

Diagn Cytopathol

DOI

ISSN

8755-1039

Publication Date

January 2002

Volume

26

Issue

1

Start / End Page

45 / 48

Location

United States

Related Subject Headings

  • Retrospective Studies
  • Reproducibility of Results
  • Referral and Consultation
  • Quality Assurance, Health Care
  • Pathology, Surgical
  • Pathology
  • Humans
  • Female
  • Diagnostic Errors
  • Biopsy, Needle
 

Citation

APA
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ICMJE
MLA
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Layfield, L. J., Jones, C., Rowe, L., & Gopez, E. V. (2002). Institutional review of outside cytology materials: a retrospective analysis of two institutions' experiences. Diagn Cytopathol, 26(1), 45–48. https://doi.org/10.1002/dc.10022
Layfield, Lester J., Claudia Jones, Leslie Rowe, and Evelyn V. Gopez. “Institutional review of outside cytology materials: a retrospective analysis of two institutions' experiences.Diagn Cytopathol 26, no. 1 (January 2002): 45–48. https://doi.org/10.1002/dc.10022.
Layfield LJ, Jones C, Rowe L, Gopez EV. Institutional review of outside cytology materials: a retrospective analysis of two institutions' experiences. Diagn Cytopathol. 2002 Jan;26(1):45–8.
Layfield, Lester J., et al. “Institutional review of outside cytology materials: a retrospective analysis of two institutions' experiences.Diagn Cytopathol, vol. 26, no. 1, Jan. 2002, pp. 45–48. Pubmed, doi:10.1002/dc.10022.
Layfield LJ, Jones C, Rowe L, Gopez EV. Institutional review of outside cytology materials: a retrospective analysis of two institutions' experiences. Diagn Cytopathol. 2002 Jan;26(1):45–48.
Journal cover image

Published In

Diagn Cytopathol

DOI

ISSN

8755-1039

Publication Date

January 2002

Volume

26

Issue

1

Start / End Page

45 / 48

Location

United States

Related Subject Headings

  • Retrospective Studies
  • Reproducibility of Results
  • Referral and Consultation
  • Quality Assurance, Health Care
  • Pathology, Surgical
  • Pathology
  • Humans
  • Female
  • Diagnostic Errors
  • Biopsy, Needle