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Acute hydrocephalus in nonketotic hyperglycinemia.

Publication ,  Journal Article
Van Hove, JL; Kishnani, PS; Demaerel, P; Kahler, SG; Miller, C; Jaeken, J; Rutledge, SL
Published in: Neurology
February 8, 2000
Published version (DOI) Link to item

We present four patients with typical neonatal onset non-ketotic hyperglycinemia (NKH) who developed hydrocephalus requiring shunting in early infancy. Brain imaging revealed acute hydrocephalus, a megacisterna magna or posterior fossa cyst, pronounced atrophy of the white matter, and an extremely thin corpus callosum in all. The three older patients had profound developmental disabilities. This suggests that the development of hydrocephalus in NKH is an additional poor prognostic sign.

Duke Scholars

Priya Sunil Kishnani
Author Priya Sunil Kishnani Pediatrics, Medical Genetics

Published In

Neurology

DOI

10.1212/wnl.54.3.754

ISSN

0028-3878

Publication Date

February 8, 2000

Volume

54

Issue

3

Start / End Page

754 / 756

Location

United States

Related Subject Headings

  • Tomography, X-Ray Computed
  • Neurology & Neurosurgery
  • Male
  • Magnetic Resonance Imaging
  • Infant, Newborn
  • Hyperglycinemia, Nonketotic
  • Hydrocephalus
  • Humans
  • Female
  • Brain
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Van Hove, J. L., Kishnani, P. S., Demaerel, P., Kahler, S. G., Miller, C., Jaeken, J., & Rutledge, S. L. (2000). Acute hydrocephalus in nonketotic hyperglycinemia. Neurology, 54(3), 754–756. https://doi.org/10.1212/wnl.54.3.754
Van Hove, J. L., P. S. Kishnani, P. Demaerel, S. G. Kahler, C. Miller, J. Jaeken, and S. L. Rutledge. “Acute hydrocephalus in nonketotic hyperglycinemia.” Neurology 54, no. 3 (February 8, 2000): 754–56. https://doi.org/10.1212/wnl.54.3.754.
Van Hove JL, Kishnani PS, Demaerel P, Kahler SG, Miller C, Jaeken J, et al. Acute hydrocephalus in nonketotic hyperglycinemia. Neurology. 2000 Feb 8;54(3):754–6.
Van Hove, J. L., et al. “Acute hydrocephalus in nonketotic hyperglycinemia.” Neurology, vol. 54, no. 3, Feb. 2000, pp. 754–56. Pubmed, doi:10.1212/wnl.54.3.754.
Van Hove JL, Kishnani PS, Demaerel P, Kahler SG, Miller C, Jaeken J, Rutledge SL. Acute hydrocephalus in nonketotic hyperglycinemia. Neurology. 2000 Feb 8;54(3):754–756.

Published In

Neurology

DOI

10.1212/wnl.54.3.754

ISSN

0028-3878

Publication Date

February 8, 2000

Volume

54

Issue

3

Start / End Page

754 / 756

Location

United States

Related Subject Headings

  • Tomography, X-Ray Computed
  • Neurology & Neurosurgery
  • Male
  • Magnetic Resonance Imaging
  • Infant, Newborn
  • Hyperglycinemia, Nonketotic
  • Hydrocephalus
  • Humans
  • Female
  • Brain