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Developmental implications of changing trajectories of IQ in males with fragile X syndrome.

Publication ,  Journal Article
Hodapp, RM; Dykens, EM; Hagerman, RJ; Schreiner, R; Lachiewicz, AM; Leckman, JF
Published in: J Am Acad Child Adolesc Psychiatry
March 1990

This study examined the trajectories of cognitive development in boys under the age of 21 years with fragile X syndrome. By combining information from three centers, data from 66 boys were analyzed; only children who had been tested two or more times with the same psychometric instrument at one or more year intervals were included in this study. Results demonstrated that males with fragile X syndrome show a decline in IQ scores, with the most marked declines seen during the early pubertal period. All 22 children retested during the 11- to 15-year period showed IQ declines, suggesting a slowing of development associated with the onset of puberty. Before age 10 years, males with higher (as opposed to lower) pretest IQs were more likely to decline at subsequent testings. A single etiological factor may not be sufficient to account for the observed findings, as both changes in neurobiological- and task-related factors seem implicated in the slowing intellectual development of this population.

Duke Scholars

Published In

J Am Acad Child Adolesc Psychiatry

DOI

ISSN

0890-8567

Publication Date

March 1990

Volume

29

Issue

2

Start / End Page

214 / 219

Location

United States

Related Subject Headings

  • Wechsler Scales
  • Stanford-Binet Test
  • Sex Chromosome Aberrations
  • Male
  • Intelligence
  • Humans
  • Fragile X Syndrome
  • Follow-Up Studies
  • Developmental & Child Psychology
  • Child, Preschool
 

Citation

APA
Chicago
ICMJE
MLA
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Hodapp, R. M., Dykens, E. M., Hagerman, R. J., Schreiner, R., Lachiewicz, A. M., & Leckman, J. F. (1990). Developmental implications of changing trajectories of IQ in males with fragile X syndrome. J Am Acad Child Adolesc Psychiatry, 29(2), 214–219. https://doi.org/10.1097/00004583-199003000-00009
Hodapp, R. M., E. M. Dykens, R. J. Hagerman, R. Schreiner, A. M. Lachiewicz, and J. F. Leckman. “Developmental implications of changing trajectories of IQ in males with fragile X syndrome.J Am Acad Child Adolesc Psychiatry 29, no. 2 (March 1990): 214–19. https://doi.org/10.1097/00004583-199003000-00009.
Hodapp RM, Dykens EM, Hagerman RJ, Schreiner R, Lachiewicz AM, Leckman JF. Developmental implications of changing trajectories of IQ in males with fragile X syndrome. J Am Acad Child Adolesc Psychiatry. 1990 Mar;29(2):214–9.
Hodapp, R. M., et al. “Developmental implications of changing trajectories of IQ in males with fragile X syndrome.J Am Acad Child Adolesc Psychiatry, vol. 29, no. 2, Mar. 1990, pp. 214–19. Pubmed, doi:10.1097/00004583-199003000-00009.
Hodapp RM, Dykens EM, Hagerman RJ, Schreiner R, Lachiewicz AM, Leckman JF. Developmental implications of changing trajectories of IQ in males with fragile X syndrome. J Am Acad Child Adolesc Psychiatry. 1990 Mar;29(2):214–219.
Journal cover image

Published In

J Am Acad Child Adolesc Psychiatry

DOI

ISSN

0890-8567

Publication Date

March 1990

Volume

29

Issue

2

Start / End Page

214 / 219

Location

United States

Related Subject Headings

  • Wechsler Scales
  • Stanford-Binet Test
  • Sex Chromosome Aberrations
  • Male
  • Intelligence
  • Humans
  • Fragile X Syndrome
  • Follow-Up Studies
  • Developmental & Child Psychology
  • Child, Preschool