Comparison of the roles of calcineurin in physiology and virulence in serotype D and serotype A strains of Cryptococcus neoformans.
Publication
, Journal Article
Cruz, MC; Sia, RA; Olson, M; Cox, GM; Heitman, J
Published in: Infect Immun
February 2000
The calcineurin gene was cloned and disrupted in serotype D strains of Cryptococcus neoformans. Serotype A and serotype D calcineurin mutants were inviable at 37 degrees C and avirulent in mice, whereas only serotype A mutants were cation stress sensitive. Thus, calcineurin plays conserved and divergent roles in serotype A and serotype D strains.
Duke Scholars
Published In
Infect Immun
DOI
ISSN
0019-9567
Publication Date
February 2000
Volume
68
Issue
2
Start / End Page
982 / 985
Location
United States
Related Subject Headings
- Virulence
- Serotyping
- Mutation
- Molecular Sequence Data
- Microbiology
- Mice, Inbred BALB C
- Mice
- Cryptococcus neoformans
- Calcineurin
- Base Sequence
Citation
APA
Chicago
ICMJE
MLA
NLM
Cruz, M. C., Sia, R. A., Olson, M., Cox, G. M., & Heitman, J. (2000). Comparison of the roles of calcineurin in physiology and virulence in serotype D and serotype A strains of Cryptococcus neoformans. Infect Immun, 68(2), 982–985. https://doi.org/10.1128/IAI.68.2.982-985.2000
Cruz, M. C., R. A. Sia, M. Olson, G. M. Cox, and J. Heitman. “Comparison of the roles of calcineurin in physiology and virulence in serotype D and serotype A strains of Cryptococcus neoformans.” Infect Immun 68, no. 2 (February 2000): 982–85. https://doi.org/10.1128/IAI.68.2.982-985.2000.
Cruz MC, Sia RA, Olson M, Cox GM, Heitman J. Comparison of the roles of calcineurin in physiology and virulence in serotype D and serotype A strains of Cryptococcus neoformans. Infect Immun. 2000 Feb;68(2):982–5.
Cruz, M. C., et al. “Comparison of the roles of calcineurin in physiology and virulence in serotype D and serotype A strains of Cryptococcus neoformans.” Infect Immun, vol. 68, no. 2, Feb. 2000, pp. 982–85. Pubmed, doi:10.1128/IAI.68.2.982-985.2000.
Cruz MC, Sia RA, Olson M, Cox GM, Heitman J. Comparison of the roles of calcineurin in physiology and virulence in serotype D and serotype A strains of Cryptococcus neoformans. Infect Immun. 2000 Feb;68(2):982–985.
Published In
Infect Immun
DOI
ISSN
0019-9567
Publication Date
February 2000
Volume
68
Issue
2
Start / End Page
982 / 985
Location
United States
Related Subject Headings
- Virulence
- Serotyping
- Mutation
- Molecular Sequence Data
- Microbiology
- Mice, Inbred BALB C
- Mice
- Cryptococcus neoformans
- Calcineurin
- Base Sequence