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Controlled evaluation of BacT/Alert standard aerobic and FAN aerobic blood culture bottles for detection of bacteremia and fungemia.

Publication ,  Journal Article
Weinstein, MP; Mirrett, S; Reimer, LG; Wilson, ML; Smith-Elekes, S; Chuard, CR; Joho, KL; Reller, LB
Published in: J Clin Microbiol
April 1995

A new medium, FAN, designed to enhance the recovery of microorganisms, has been developed for the BacT/Alert blood culture system (Organon Teknika Corp., Durham, N.C.). We compared the yield and speed of detection of microorganisms in 6,847 adequately filled paired aerobic standard and FAN bottles at four university hospitals. Of 499 clinically significant microorganisms isolated from one or both bottles, significantly more Staphylococcus aureus isolates (P < 0.001), coagulase-negative staphylococci (P < 0.001), yeasts (P < 0.01), and all microorganisms combined (P < 0.001) were recovered from the FAN bottles. Overall, the speeds of detection of positive cultures did not differ between the two medium formulations; mean times to detection in the standard and FAN bottles were 16.1 and 16.0 h, respectively. When a subset of patients on antimicrobial therapy was evaluated, significantly enhanced yield from the FAN bottle was evident for staphylococci. Overall, the FAN bottle outperformed the standard aerobic BacT/Alert bottle.

Duke Scholars

Published In

J Clin Microbiol

DOI

ISSN

0095-1137

Publication Date

April 1995

Volume

33

Issue

4

Start / End Page

978 / 981

Location

United States

Related Subject Headings

  • Time Factors
  • Mycology
  • Microbiology
  • Humans
  • Fungi
  • Fungemia
  • Evaluation Studies as Topic
  • Diagnostic Errors
  • Culture Media
  • Bacteriological Techniques
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Weinstein, M. P., Mirrett, S., Reimer, L. G., Wilson, M. L., Smith-Elekes, S., Chuard, C. R., … Reller, L. B. (1995). Controlled evaluation of BacT/Alert standard aerobic and FAN aerobic blood culture bottles for detection of bacteremia and fungemia. J Clin Microbiol, 33(4), 978–981. https://doi.org/10.1128/jcm.33.4.978-981.1995
Weinstein, M. P., S. Mirrett, L. G. Reimer, M. L. Wilson, S. Smith-Elekes, C. R. Chuard, K. L. Joho, and L. B. Reller. “Controlled evaluation of BacT/Alert standard aerobic and FAN aerobic blood culture bottles for detection of bacteremia and fungemia.J Clin Microbiol 33, no. 4 (April 1995): 978–81. https://doi.org/10.1128/jcm.33.4.978-981.1995.
Weinstein MP, Mirrett S, Reimer LG, Wilson ML, Smith-Elekes S, Chuard CR, et al. Controlled evaluation of BacT/Alert standard aerobic and FAN aerobic blood culture bottles for detection of bacteremia and fungemia. J Clin Microbiol. 1995 Apr;33(4):978–81.
Weinstein, M. P., et al. “Controlled evaluation of BacT/Alert standard aerobic and FAN aerobic blood culture bottles for detection of bacteremia and fungemia.J Clin Microbiol, vol. 33, no. 4, Apr. 1995, pp. 978–81. Pubmed, doi:10.1128/jcm.33.4.978-981.1995.
Weinstein MP, Mirrett S, Reimer LG, Wilson ML, Smith-Elekes S, Chuard CR, Joho KL, Reller LB. Controlled evaluation of BacT/Alert standard aerobic and FAN aerobic blood culture bottles for detection of bacteremia and fungemia. J Clin Microbiol. 1995 Apr;33(4):978–981.

Published In

J Clin Microbiol

DOI

ISSN

0095-1137

Publication Date

April 1995

Volume

33

Issue

4

Start / End Page

978 / 981

Location

United States

Related Subject Headings

  • Time Factors
  • Mycology
  • Microbiology
  • Humans
  • Fungi
  • Fungemia
  • Evaluation Studies as Topic
  • Diagnostic Errors
  • Culture Media
  • Bacteriological Techniques