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Short-course therapy for catheter-associated Staphylococcus aureus bacteremia.

Publication ,  Journal Article
Ehni, WF; Reller, LB
Published in: Arch Intern Med
March 1989

To determine the efficacy of "short-course" therapy (less than 17 days) for Staphylococcus aureus catheter-associated bacteremia, 13 patients were prospectively followed up for at least three months after completion of therapy. A single patient relapsed after 28 days with endocarditis. No clinical or microbiological predictors of relapse could be identified, and coexistent medical conditions associated with some degree of immunosuppression did not appear to predispose to relapse. The results of this study and a review of the literature indicate that short-course therapy for uncomplicated S aureus catheter-associated bacteremia has a relapse rate of only 5% to 10% and, therefore, is reasonable therapy for this condition. The majority of relapses are endocarditis and occur within ten weeks after completion of therapy. Close follow-up during this period is essential.

Duke Scholars

Published In

Arch Intern Med

ISSN

0003-9926

Publication Date

March 1989

Volume

149

Issue

3

Start / End Page

533 / 536

Location

United States

Related Subject Headings

  • Vancomycin
  • Time Factors
  • Staphylococcal Infections
  • Sepsis
  • Risk Factors
  • Recurrence
  • Prospective Studies
  • Oxacillin
  • Humans
  • General & Internal Medicine
 

Citation

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MLA
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Ehni, W. F., & Reller, L. B. (1989). Short-course therapy for catheter-associated Staphylococcus aureus bacteremia. Arch Intern Med, 149(3), 533–536.
Ehni, W. F., and L. B. Reller. “Short-course therapy for catheter-associated Staphylococcus aureus bacteremia.Arch Intern Med 149, no. 3 (March 1989): 533–36.
Ehni WF, Reller LB. Short-course therapy for catheter-associated Staphylococcus aureus bacteremia. Arch Intern Med. 1989 Mar;149(3):533–6.
Ehni, W. F., and L. B. Reller. “Short-course therapy for catheter-associated Staphylococcus aureus bacteremia.Arch Intern Med, vol. 149, no. 3, Mar. 1989, pp. 533–36.
Ehni WF, Reller LB. Short-course therapy for catheter-associated Staphylococcus aureus bacteremia. Arch Intern Med. 1989 Mar;149(3):533–536.

Published In

Arch Intern Med

ISSN

0003-9926

Publication Date

March 1989

Volume

149

Issue

3

Start / End Page

533 / 536

Location

United States

Related Subject Headings

  • Vancomycin
  • Time Factors
  • Staphylococcal Infections
  • Sepsis
  • Risk Factors
  • Recurrence
  • Prospective Studies
  • Oxacillin
  • Humans
  • General & Internal Medicine