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Molecular cloning and sequencing of DNA complementary to chicken liver fatty acid synthase mRNA.

Publication ,  Journal Article
Yuan, ZY; Liu, W; Hammes, GG
Published in: Proc Natl Acad Sci U S A
September 1988

The cDNA corresponding to 4.18 kilobases (kb) of the mRNA of chicken liver fatty acid synthase has been cloned and sequenced. The cDNA corresponds to the 3' end of the mRNA and consists of a 1.87-kb noncoding tail and a 2.31-kb region encoding 769 amino acids of the C terminus of the enzyme. The thioesterase at the C terminus, preceded by the acyl carrier protein, can be identified from known amino acid sequences. However, the identity of the enzymes N terminal to the acyl carrier protein could not be ascertained. The partial amino acid sequence of the chicken liver fatty acid synthase shows greater than 70% similarity with the rat mammary gland enzyme.

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Published In

Proc Natl Acad Sci U S A

DOI

ISSN

0027-8424

Publication Date

September 1988

Volume

85

Issue

17

Start / End Page

6328 / 6331

Location

United States

Related Subject Headings

  • RNA, Messenger
  • Molecular Sequence Data
  • Male
  • Liver
  • Genes
  • Fatty Acid Synthases
  • DNA Restriction Enzymes
  • DNA
  • Cloning, Molecular
  • Chickens
 

Citation

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Yuan, Z. Y., Liu, W., & Hammes, G. G. (1988). Molecular cloning and sequencing of DNA complementary to chicken liver fatty acid synthase mRNA. Proc Natl Acad Sci U S A, 85(17), 6328–6331. https://doi.org/10.1073/pnas.85.17.6328
Yuan, Z. Y., W. Liu, and G. G. Hammes. “Molecular cloning and sequencing of DNA complementary to chicken liver fatty acid synthase mRNA.Proc Natl Acad Sci U S A 85, no. 17 (September 1988): 6328–31. https://doi.org/10.1073/pnas.85.17.6328.
Yuan ZY, Liu W, Hammes GG. Molecular cloning and sequencing of DNA complementary to chicken liver fatty acid synthase mRNA. Proc Natl Acad Sci U S A. 1988 Sep;85(17):6328–31.
Yuan, Z. Y., et al. “Molecular cloning and sequencing of DNA complementary to chicken liver fatty acid synthase mRNA.Proc Natl Acad Sci U S A, vol. 85, no. 17, Sept. 1988, pp. 6328–31. Pubmed, doi:10.1073/pnas.85.17.6328.
Yuan ZY, Liu W, Hammes GG. Molecular cloning and sequencing of DNA complementary to chicken liver fatty acid synthase mRNA. Proc Natl Acad Sci U S A. 1988 Sep;85(17):6328–6331.
Journal cover image

Published In

Proc Natl Acad Sci U S A

DOI

ISSN

0027-8424

Publication Date

September 1988

Volume

85

Issue

17

Start / End Page

6328 / 6331

Location

United States

Related Subject Headings

  • RNA, Messenger
  • Molecular Sequence Data
  • Male
  • Liver
  • Genes
  • Fatty Acid Synthases
  • DNA Restriction Enzymes
  • DNA
  • Cloning, Molecular
  • Chickens