Umbilical cord blood hematopoietic stem and repopulating cells in human clinical transplantation.
Publication
, Journal Article
Broxmeyer, HE; Kurtzberg, J; Gluckman, E; Auerbach, AD; Douglas, G; Cooper, S; Falkenburg, JH; Bard, J; Boyse, EA
Published in: Blood Cells
1991
This paper reviews our recent laboratory and clinical studies demonstrating the efficacious use of human umbilical cord blood for HLA-matched allogeneic sibling stem/progenitor cell transplantation in cases of Fanconi's anemia. Future implications and potential problems are discussed with regards to (a) the possibility of maternal cell contamination, (b) the broadness of applicability with regards to other diseases that might be transplanted, and whether such transplants are feasible in adults, as well as in children, and (c) the immunological reactivity of cord blood cells, and whether these cells can be used to cross histocompatibility barriers more easily than that of bone marrow from adults.
Duke Scholars
Published In
Blood Cells
ISSN
0340-4684
Publication Date
1991
Volume
17
Issue
2
Start / End Page
313 / 329
Location
United States
Related Subject Headings
- Pregnancy
- Mice
- Humans
- Hematopoietic Stem Cell Transplantation
- Hematopoiesis
- Graft vs Host Disease
- Fetus
- Fetal Blood
- Female
- Fanconi Anemia
Citation
APA
Chicago
ICMJE
MLA
NLM
Broxmeyer, H. E., Kurtzberg, J., Gluckman, E., Auerbach, A. D., Douglas, G., Cooper, S., … Boyse, E. A. (1991). Umbilical cord blood hematopoietic stem and repopulating cells in human clinical transplantation. Blood Cells, 17(2), 313–329.
Broxmeyer, H. E., J. Kurtzberg, E. Gluckman, A. D. Auerbach, G. Douglas, S. Cooper, J. H. Falkenburg, J. Bard, and E. A. Boyse. “Umbilical cord blood hematopoietic stem and repopulating cells in human clinical transplantation.” Blood Cells 17, no. 2 (1991): 313–29.
Broxmeyer HE, Kurtzberg J, Gluckman E, Auerbach AD, Douglas G, Cooper S, et al. Umbilical cord blood hematopoietic stem and repopulating cells in human clinical transplantation. Blood Cells. 1991;17(2):313–29.
Broxmeyer, H. E., et al. “Umbilical cord blood hematopoietic stem and repopulating cells in human clinical transplantation.” Blood Cells, vol. 17, no. 2, 1991, pp. 313–29.
Broxmeyer HE, Kurtzberg J, Gluckman E, Auerbach AD, Douglas G, Cooper S, Falkenburg JH, Bard J, Boyse EA. Umbilical cord blood hematopoietic stem and repopulating cells in human clinical transplantation. Blood Cells. 1991;17(2):313–329.
Published In
Blood Cells
ISSN
0340-4684
Publication Date
1991
Volume
17
Issue
2
Start / End Page
313 / 329
Location
United States
Related Subject Headings
- Pregnancy
- Mice
- Humans
- Hematopoietic Stem Cell Transplantation
- Hematopoiesis
- Graft vs Host Disease
- Fetus
- Fetal Blood
- Female
- Fanconi Anemia