Differential diagnosis and pathophysiology of Cushing's syndrome and primary affective disorder.
Publication
, Journal Article
Krystal, A; Krishnan, KR; Raitiere, M; Poland, R; Ritchie, JC; Dunnick, NR; Hanada, K; Nemeroff, CB
Published in: J Neuropsychiatry Clin Neurosci
1990
Most patients with major depression have increased 24-hour urinary free cortisol and cortisol nonsuppression after dexamethasone administration, which are cornerstones of a diagnosis of Cushing's syndrome. Similarly, Cushing's syndrome patients often suffer from major psychiatric syndromes, most often depression. These similarities between the two conditions sometimes make it difficult to differentiate them and have led some investigators to suggest they are two points on a spectrum of endocrinologic dysfunction. This article reviews the literature comparing Cushing's syndrome and primary affective disorder and presents two cases that illustrate just how closely these diseases may resemble one another.
Duke Scholars
Published In
J Neuropsychiatry Clin Neurosci
DOI
ISSN
0895-0172
Publication Date
1990
Volume
2
Issue
1
Start / End Page
34 / 43
Location
United States
Related Subject Headings
- Tomography, X-Ray Computed
- Psychotropic Drugs
- Psychiatry
- Neurocognitive Disorders
- Middle Aged
- Hydrocortisone
- Humans
- Female
- Diagnosis, Differential
- Depressive Disorder
Citation
APA
Chicago
ICMJE
MLA
NLM
Krystal, A., Krishnan, K. R., Raitiere, M., Poland, R., Ritchie, J. C., Dunnick, N. R., … Nemeroff, C. B. (1990). Differential diagnosis and pathophysiology of Cushing's syndrome and primary affective disorder. J Neuropsychiatry Clin Neurosci, 2(1), 34–43. https://doi.org/10.1176/jnp.2.1.34
Krystal, A., K. R. Krishnan, M. Raitiere, R. Poland, J. C. Ritchie, N. R. Dunnick, K. Hanada, and C. B. Nemeroff. “Differential diagnosis and pathophysiology of Cushing's syndrome and primary affective disorder.” J Neuropsychiatry Clin Neurosci 2, no. 1 (1990): 34–43. https://doi.org/10.1176/jnp.2.1.34.
Krystal A, Krishnan KR, Raitiere M, Poland R, Ritchie JC, Dunnick NR, et al. Differential diagnosis and pathophysiology of Cushing's syndrome and primary affective disorder. J Neuropsychiatry Clin Neurosci. 1990;2(1):34–43.
Krystal, A., et al. “Differential diagnosis and pathophysiology of Cushing's syndrome and primary affective disorder.” J Neuropsychiatry Clin Neurosci, vol. 2, no. 1, 1990, pp. 34–43. Pubmed, doi:10.1176/jnp.2.1.34.
Krystal A, Krishnan KR, Raitiere M, Poland R, Ritchie JC, Dunnick NR, Hanada K, Nemeroff CB. Differential diagnosis and pathophysiology of Cushing's syndrome and primary affective disorder. J Neuropsychiatry Clin Neurosci. 1990;2(1):34–43.
Published In
J Neuropsychiatry Clin Neurosci
DOI
ISSN
0895-0172
Publication Date
1990
Volume
2
Issue
1
Start / End Page
34 / 43
Location
United States
Related Subject Headings
- Tomography, X-Ray Computed
- Psychotropic Drugs
- Psychiatry
- Neurocognitive Disorders
- Middle Aged
- Hydrocortisone
- Humans
- Female
- Diagnosis, Differential
- Depressive Disorder