Novel 3',5'-cyclic nucleotide analogue: adenosine 3',5'-cyclic boranomonophosphate.
Publication
, Journal Article
Lin, J; He, K; Shaw, BR
Published in: Organic letters
March 2001
A general procedure for the first synthesis of a 3',5'-cyclic boranomonophosphate was established. Specifically, adenosine 3',5'-cyclic boranomonophosphosphate (cyclic AMPB, 4c), a P-borane (BH(3)) analogue of adenosine 3',5'-cyclic monophosphate (cAMP), was synthesized via a phosphite approach in good yield. The method is also applicable for syntheses of natural cAMP and its phosphorothioate analogue. The two diasteromers of cyclic AMPB 4c were separated, and their chemical structures were established via spectroscopic methods.
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Published In
Organic letters
DOI
EISSN
1523-7052
ISSN
1523-7060
Publication Date
March 2001
Volume
3
Issue
6
Start / End Page
795 / 797
Related Subject Headings
- Stereoisomerism
- Phosphates
- Organic Chemistry
- Molecular Structure
- Indicators and Reagents
- Cyclic AMP
- Boron Compounds
- 03 Chemical Sciences
Citation
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ICMJE
MLA
NLM
Lin, J., He, K., & Shaw, B. R. (2001). Novel 3',5'-cyclic nucleotide analogue: adenosine 3',5'-cyclic boranomonophosphate. Organic Letters, 3(6), 795–797. https://doi.org/10.1021/ol0003230
Lin, J., K. He, and B. R. Shaw. “Novel 3',5'-cyclic nucleotide analogue: adenosine 3',5'-cyclic boranomonophosphate.” Organic Letters 3, no. 6 (March 2001): 795–97. https://doi.org/10.1021/ol0003230.
Lin J, He K, Shaw BR. Novel 3',5'-cyclic nucleotide analogue: adenosine 3',5'-cyclic boranomonophosphate. Organic letters. 2001 Mar;3(6):795–7.
Lin, J., et al. “Novel 3',5'-cyclic nucleotide analogue: adenosine 3',5'-cyclic boranomonophosphate.” Organic Letters, vol. 3, no. 6, Mar. 2001, pp. 795–97. Epmc, doi:10.1021/ol0003230.
Lin J, He K, Shaw BR. Novel 3',5'-cyclic nucleotide analogue: adenosine 3',5'-cyclic boranomonophosphate. Organic letters. 2001 Mar;3(6):795–797.
Published In
Organic letters
DOI
EISSN
1523-7052
ISSN
1523-7060
Publication Date
March 2001
Volume
3
Issue
6
Start / End Page
795 / 797
Related Subject Headings
- Stereoisomerism
- Phosphates
- Organic Chemistry
- Molecular Structure
- Indicators and Reagents
- Cyclic AMP
- Boron Compounds
- 03 Chemical Sciences