Enantioselective syntheses of homophenylalanine derivatives via nitrone 1,3-dipolar cycloaddition reactions with styrenes
Publication
, Journal Article
Long, A; Baldwin, SW
Published in: Tetrahedron Letters
August 6, 2001
A new two-step route to derivatives of homophenylalanine is presented. Cycloaddition of a cyclic nitrone glycine template with various styrene derivatives affords good yields of 5-substituted cycloadducts. One-step hydrogenolysis (three bonds) then affords the optically pure α-amino acids related to homophenylalanine. © 2001 Published by Elsevier Science Ltd.
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Published In
Tetrahedron Letters
DOI
ISSN
0040-4039
Publication Date
August 6, 2001
Volume
42
Issue
32
Start / End Page
5343 / 5345
Related Subject Headings
- Organic Chemistry
- 3405 Organic chemistry
- 3404 Medicinal and biomolecular chemistry
- 3101 Biochemistry and cell biology
- 0305 Organic Chemistry
- 0304 Medicinal and Biomolecular Chemistry
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Long, A., & Baldwin, S. W. (2001). Enantioselective syntheses of homophenylalanine derivatives via nitrone 1,3-dipolar cycloaddition reactions with styrenes. Tetrahedron Letters, 42(32), 5343–5345. https://doi.org/10.1016/S0040-4039(01)00821-8
Long, A., and S. W. Baldwin. “Enantioselective syntheses of homophenylalanine derivatives via nitrone 1,3-dipolar cycloaddition reactions with styrenes.” Tetrahedron Letters 42, no. 32 (August 6, 2001): 5343–45. https://doi.org/10.1016/S0040-4039(01)00821-8.
Long A, Baldwin SW. Enantioselective syntheses of homophenylalanine derivatives via nitrone 1,3-dipolar cycloaddition reactions with styrenes. Tetrahedron Letters. 2001 Aug 6;42(32):5343–5.
Long, A., and S. W. Baldwin. “Enantioselective syntheses of homophenylalanine derivatives via nitrone 1,3-dipolar cycloaddition reactions with styrenes.” Tetrahedron Letters, vol. 42, no. 32, Aug. 2001, pp. 5343–45. Scopus, doi:10.1016/S0040-4039(01)00821-8.
Long A, Baldwin SW. Enantioselective syntheses of homophenylalanine derivatives via nitrone 1,3-dipolar cycloaddition reactions with styrenes. Tetrahedron Letters. 2001 Aug 6;42(32):5343–5345.
Published In
Tetrahedron Letters
DOI
ISSN
0040-4039
Publication Date
August 6, 2001
Volume
42
Issue
32
Start / End Page
5343 / 5345
Related Subject Headings
- Organic Chemistry
- 3405 Organic chemistry
- 3404 Medicinal and biomolecular chemistry
- 3101 Biochemistry and cell biology
- 0305 Organic Chemistry
- 0304 Medicinal and Biomolecular Chemistry