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Use of SDS micelles to stabilize a ternary intermediate in the reaction of ferrioxamine B and 1,10-phenanthroline.

Publication ,  Journal Article
Olmstead, EG; Harman, SW; Choo, PL; Crumbliss, AL
Published in: Inorganic chemistry
October 2001

Spectrophotometric measurements of the reaction of ferrioxamine B (FeHDFB(+)) with 1,10-phenanthroline (phen) reveal the presence of a ternary intermediate complex in both aqueous solution and an aqueous solution of 0.16 M sodium dodecyl sulfate (SDS). The stoichiometry of the intermediate is Fe(H(2)DFB)(phen)(2+) on the basis of a Schwarzenbach analysis of spectrophotometric data obtained at variable pH and phen concentrations. The ternary complex formation constant for the reaction FeHDFB(+) + H(+) + phen right arrow over left arrow Fe(H(2)DFB)(phen)(2+) is log K = 6.96 in aqueous solution and log K = 8.64 in aqueous 0.16 M SDS. The enhanced stability of Fe(H(2)DFB)(phen)(2+) in micellar solution was analyzed in terms of the pseudophase ion-exchange (PPIE) model of micellar reactions. The association constants for the binding of each reactant to the micellar pseudophase were measured by ultrafiltration. According to PPIE model calculations, the enhanced stability of Fe(H(2)DFB)(phen)(2+) in micellar SDS arises from a proximity effect created by the high local concentrations of reactants in the micellar pseudophase. The calculations also indicate that an inhibitory medium or compartmentalization effect is operative since the observed micellar enhancement is much smaller than predicted by the PPIE model. The micellar stabilization of the Fe(H(2)DFB)(phen)(2+) intermediate and the overall conversion of FeHDFB(+) to Fe(phen)(3)(2+) are discussed as a possible model system for siderophore iron release in microbial organisms.

Duke Scholars

Published In

Inorganic chemistry

DOI

EISSN

1520-510X

ISSN

0020-1669

Publication Date

October 2001

Volume

40

Issue

21

Start / End Page

5420 / 5427

Related Subject Headings

  • Water
  • Sodium Dodecyl Sulfate
  • Siderophores
  • Phenanthrolines
  • Molecular Mimicry
  • Micelles
  • Kinetics
  • Iron
  • Inorganic & Nuclear Chemistry
  • Ferric Compounds
 

Citation

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Olmstead, E. G., Harman, S. W., Choo, P. L., & Crumbliss, A. L. (2001). Use of SDS micelles to stabilize a ternary intermediate in the reaction of ferrioxamine B and 1,10-phenanthroline. Inorganic Chemistry, 40(21), 5420–5427. https://doi.org/10.1021/ic0008621
Olmstead, E. G., S. W. Harman, P. L. Choo, and A. L. Crumbliss. “Use of SDS micelles to stabilize a ternary intermediate in the reaction of ferrioxamine B and 1,10-phenanthroline.Inorganic Chemistry 40, no. 21 (October 2001): 5420–27. https://doi.org/10.1021/ic0008621.
Olmstead EG, Harman SW, Choo PL, Crumbliss AL. Use of SDS micelles to stabilize a ternary intermediate in the reaction of ferrioxamine B and 1,10-phenanthroline. Inorganic chemistry. 2001 Oct;40(21):5420–7.
Olmstead, E. G., et al. “Use of SDS micelles to stabilize a ternary intermediate in the reaction of ferrioxamine B and 1,10-phenanthroline.Inorganic Chemistry, vol. 40, no. 21, Oct. 2001, pp. 5420–27. Epmc, doi:10.1021/ic0008621.
Olmstead EG, Harman SW, Choo PL, Crumbliss AL. Use of SDS micelles to stabilize a ternary intermediate in the reaction of ferrioxamine B and 1,10-phenanthroline. Inorganic chemistry. 2001 Oct;40(21):5420–5427.
Journal cover image

Published In

Inorganic chemistry

DOI

EISSN

1520-510X

ISSN

0020-1669

Publication Date

October 2001

Volume

40

Issue

21

Start / End Page

5420 / 5427

Related Subject Headings

  • Water
  • Sodium Dodecyl Sulfate
  • Siderophores
  • Phenanthrolines
  • Molecular Mimicry
  • Micelles
  • Kinetics
  • Iron
  • Inorganic & Nuclear Chemistry
  • Ferric Compounds