Synthesis of a novel triphosphate analogue: Nucleoside α-P-borano, α-P-thiotriphosphate
Publication
, Journal Article
Lin, J; Shaw, BR
Published in: Chemical Communications
November 7, 2000
The first boranothiotriphosphate compound, thymidine 5'-[α-P-borano, α-P-thio]triphosphate, in which borane and sulfur replace the two non-bridging oxygens of the α-phosphate in natural nucleoside triphosphates (NTPs), has been synthesized; some chemical properties of this borane-sulfur disubstituted nucleoside triphosphate analogue have been investigated. The synthetic approach reported here should be applicable for preparation of any α-borano, α-thio modified NTP or deoxy NTP; potential applications are discussed.
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Published In
Chemical Communications
DOI
ISSN
1359-7345
Publication Date
November 7, 2000
Issue
21
Start / End Page
2115 / 2116
Related Subject Headings
- Organic Chemistry
- 40 Engineering
- 34 Chemical sciences
- 03 Chemical Sciences
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Lin, J., & Shaw, B. R. (2000). Synthesis of a novel triphosphate analogue: Nucleoside α-P-borano, α-P-thiotriphosphate. Chemical Communications, (21), 2115–2116. https://doi.org/10.1039/b005059h
Lin, J., and B. R. Shaw. “Synthesis of a novel triphosphate analogue: Nucleoside α-P-borano, α-P-thiotriphosphate.” Chemical Communications, no. 21 (November 7, 2000): 2115–16. https://doi.org/10.1039/b005059h.
Lin J, Shaw BR. Synthesis of a novel triphosphate analogue: Nucleoside α-P-borano, α-P-thiotriphosphate. Chemical Communications. 2000 Nov 7;(21):2115–6.
Lin, J., and B. R. Shaw. “Synthesis of a novel triphosphate analogue: Nucleoside α-P-borano, α-P-thiotriphosphate.” Chemical Communications, no. 21, Nov. 2000, pp. 2115–16. Scopus, doi:10.1039/b005059h.
Lin J, Shaw BR. Synthesis of a novel triphosphate analogue: Nucleoside α-P-borano, α-P-thiotriphosphate. Chemical Communications. 2000 Nov 7;(21):2115–2116.
Published In
Chemical Communications
DOI
ISSN
1359-7345
Publication Date
November 7, 2000
Issue
21
Start / End Page
2115 / 2116
Related Subject Headings
- Organic Chemistry
- 40 Engineering
- 34 Chemical sciences
- 03 Chemical Sciences