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Stereoselective β-face catalytic hydrogenation of Δ4- 9α-fluoro-11β-hydroxycorticosteroids: Reappraisal

Publication ,  Journal Article
Shapiro, EL; Gentles, MJ; McPhail, AT; Onan, KD
Published in: Journal of the Chemical Society, Chemical Communications
December 1, 1976

At variance with previous reports, palladium-catalysed reduction of 9α-fluorohydrocortisone 21-acetate (1a) and 1,2-didehydro-9α-fluoro- 16α-methylhydrocortisone 21-acetate (2a) yields the 5β-configuration.

Duke Scholars

Published In

Journal of the Chemical Society, Chemical Communications

DOI

ISSN

0022-4936

Publication Date

December 1, 1976

Issue

23

Start / End Page

961 / 963
 

Citation

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Shapiro, E. L., Gentles, M. J., McPhail, A. T., & Onan, K. D. (1976). Stereoselective β-face catalytic hydrogenation of Δ4- 9α-fluoro-11β-hydroxycorticosteroids: Reappraisal. Journal of the Chemical Society, Chemical Communications, (23), 961–963. https://doi.org/10.1039/C39760000961
Shapiro, E. L., M. J. Gentles, A. T. McPhail, and K. D. Onan. “Stereoselective β-face catalytic hydrogenation of Δ4- 9α-fluoro-11β-hydroxycorticosteroids: Reappraisal.” Journal of the Chemical Society, Chemical Communications, no. 23 (December 1, 1976): 961–63. https://doi.org/10.1039/C39760000961.
Shapiro EL, Gentles MJ, McPhail AT, Onan KD. Stereoselective β-face catalytic hydrogenation of Δ4- 9α-fluoro-11β-hydroxycorticosteroids: Reappraisal. Journal of the Chemical Society, Chemical Communications. 1976 Dec 1;(23):961–3.
Shapiro, E. L., et al. “Stereoselective β-face catalytic hydrogenation of Δ4- 9α-fluoro-11β-hydroxycorticosteroids: Reappraisal.” Journal of the Chemical Society, Chemical Communications, no. 23, Dec. 1976, pp. 961–63. Scopus, doi:10.1039/C39760000961.
Shapiro EL, Gentles MJ, McPhail AT, Onan KD. Stereoselective β-face catalytic hydrogenation of Δ4- 9α-fluoro-11β-hydroxycorticosteroids: Reappraisal. Journal of the Chemical Society, Chemical Communications. 1976 Dec 1;(23):961–963.

Published In

Journal of the Chemical Society, Chemical Communications

DOI

ISSN

0022-4936

Publication Date

December 1, 1976

Issue

23

Start / End Page

961 / 963