Neocleordane diterpenoids and their artifacts from Teucrium olivarianum
The aerial parts of Teucrium oliverianum yielded five new neocleordane diterpenoids (teucrolins A [4], B [5], C [6], D [7], and E [8]), three neocleordane diterpene artifacts (12-O-methylteucrolivin A [9], 12-O-methylteucrolin A [10], and 12-O-ethylteucrolin A [11]), and the three known diterpenoids teucrolivins A [1], B [2], and C [3]. In addition, four other known compounds were isolated: the sterol 24(S)-stigmasta-5,22,25-trien-3β-ol, the iridoid 8-O-acetylharpagide, and the flavones eupatorin and cirsiliol. The structural assignments of all new diterpenoids and their artifacts were based on 1D and 2D nmr spectral data, chemical derivatization, and X-ray crystallographic analysis of 10; the latter established the relative stereochemistry and the presence of the rare axial substitution at C-3 in 10 and related compounds. © 1993, American Chemical Society. All rights reserved.
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- Medicinal & Biomolecular Chemistry
- 4208 Traditional, complementary and integrative medicine
- 11 Medical and Health Sciences
- 06 Biological Sciences
- 03 Chemical Sciences
Citation
Published In
DOI
EISSN
ISSN
Publication Date
Volume
Issue
Start / End Page
Related Subject Headings
- Medicinal & Biomolecular Chemistry
- 4208 Traditional, complementary and integrative medicine
- 11 Medical and Health Sciences
- 06 Biological Sciences
- 03 Chemical Sciences