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Synthesis and absolute configuration of hydroxythreonine, a biosynthetic precursor of rhizobitoxine in pseudomonas

Publication ,  Journal Article
Pirrung, MC; Nunn, DS; McPhail, AT; Mitchell, RE
Published in: Bioorganic and Medicinal Chemistry Letters
January 1, 1993

The synthesis of hydroxythreonine via osmylation of vinyl glycine has permitted a crystalline derivative to be prepared as well as comparison with naturally-derived material, allowing the assignment of the absolute configuration of the natural product as (2S, 3R). © 1993.

Duke Scholars

Published In

Bioorganic and Medicinal Chemistry Letters

DOI

ISSN

0960-894X

Publication Date

January 1, 1993

Volume

3

Issue

10

Start / End Page

2095 / 2098

Related Subject Headings

  • Medicinal & Biomolecular Chemistry
  • 3405 Organic chemistry
  • 3404 Medicinal and biomolecular chemistry
  • 1115 Pharmacology and Pharmaceutical Sciences
  • 0305 Organic Chemistry
  • 0304 Medicinal and Biomolecular Chemistry
 

Citation

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Pirrung, M. C., Nunn, D. S., McPhail, A. T., & Mitchell, R. E. (1993). Synthesis and absolute configuration of hydroxythreonine, a biosynthetic precursor of rhizobitoxine in pseudomonas. Bioorganic and Medicinal Chemistry Letters, 3(10), 2095–2098. https://doi.org/10.1016/S0960-894X(01)81024-6
Pirrung, M. C., D. S. Nunn, A. T. McPhail, and R. E. Mitchell. “Synthesis and absolute configuration of hydroxythreonine, a biosynthetic precursor of rhizobitoxine in pseudomonas.” Bioorganic and Medicinal Chemistry Letters 3, no. 10 (January 1, 1993): 2095–98. https://doi.org/10.1016/S0960-894X(01)81024-6.
Pirrung MC, Nunn DS, McPhail AT, Mitchell RE. Synthesis and absolute configuration of hydroxythreonine, a biosynthetic precursor of rhizobitoxine in pseudomonas. Bioorganic and Medicinal Chemistry Letters. 1993 Jan 1;3(10):2095–8.
Pirrung, M. C., et al. “Synthesis and absolute configuration of hydroxythreonine, a biosynthetic precursor of rhizobitoxine in pseudomonas.” Bioorganic and Medicinal Chemistry Letters, vol. 3, no. 10, Jan. 1993, pp. 2095–98. Scopus, doi:10.1016/S0960-894X(01)81024-6.
Pirrung MC, Nunn DS, McPhail AT, Mitchell RE. Synthesis and absolute configuration of hydroxythreonine, a biosynthetic precursor of rhizobitoxine in pseudomonas. Bioorganic and Medicinal Chemistry Letters. 1993 Jan 1;3(10):2095–2098.
Journal cover image

Published In

Bioorganic and Medicinal Chemistry Letters

DOI

ISSN

0960-894X

Publication Date

January 1, 1993

Volume

3

Issue

10

Start / End Page

2095 / 2098

Related Subject Headings

  • Medicinal & Biomolecular Chemistry
  • 3405 Organic chemistry
  • 3404 Medicinal and biomolecular chemistry
  • 1115 Pharmacology and Pharmaceutical Sciences
  • 0305 Organic Chemistry
  • 0304 Medicinal and Biomolecular Chemistry