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Five new modified 6,7-secolabdane diterpenoids from Cluytia richardiana

Publication ,  Journal Article
Mossa, JS; Muhammad, I; Al-Yahya, MA; Mirza, HH; El-Feraly, FS; McPhail, AT
Published in: Journal of Natural Products
March 1, 1996

The aerial parts of Cluytia richardiana yielded five new modified 6,7- secolabdane diterpene derivatives, saudinolide (4), dihydrosaudinolide (5), 5β-hydroxyrichardianidin 1 (6), and 5β-hydroxyrichardianidin 2 (7), and the 6,7-seco-6,11-cyclo-20-norlabdane cluytene F (8). The structural assignments of the diterpenoids were based on their spectral data, including 2D NMR experiments, and chemical derivatization. X-ray crystallographic analyses provided unambiguous characterization of the structures and relative stereochemistries of 4, 6, 7, and 1-O-acetylcluytene F (10).

Duke Scholars

Published In

Journal of Natural Products

DOI

ISSN

0163-3864

Publication Date

March 1, 1996

Volume

59

Issue

3

Start / End Page

224 / 231

Related Subject Headings

  • Medicinal & Biomolecular Chemistry
  • 4208 Traditional, complementary and integrative medicine
  • 11 Medical and Health Sciences
  • 06 Biological Sciences
  • 03 Chemical Sciences
 

Citation

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Mossa, J. S., Muhammad, I., Al-Yahya, M. A., Mirza, H. H., El-Feraly, F. S., & McPhail, A. T. (1996). Five new modified 6,7-secolabdane diterpenoids from Cluytia richardiana. Journal of Natural Products, 59(3), 224–231. https://doi.org/10.1021/np960119e
Mossa, J. S., I. Muhammad, M. A. Al-Yahya, H. H. Mirza, F. S. El-Feraly, and A. T. McPhail. “Five new modified 6,7-secolabdane diterpenoids from Cluytia richardiana.” Journal of Natural Products 59, no. 3 (March 1, 1996): 224–31. https://doi.org/10.1021/np960119e.
Mossa JS, Muhammad I, Al-Yahya MA, Mirza HH, El-Feraly FS, McPhail AT. Five new modified 6,7-secolabdane diterpenoids from Cluytia richardiana. Journal of Natural Products. 1996 Mar 1;59(3):224–31.
Mossa, J. S., et al. “Five new modified 6,7-secolabdane diterpenoids from Cluytia richardiana.” Journal of Natural Products, vol. 59, no. 3, Mar. 1996, pp. 224–31. Scopus, doi:10.1021/np960119e.
Mossa JS, Muhammad I, Al-Yahya MA, Mirza HH, El-Feraly FS, McPhail AT. Five new modified 6,7-secolabdane diterpenoids from Cluytia richardiana. Journal of Natural Products. 1996 Mar 1;59(3):224–231.
Journal cover image

Published In

Journal of Natural Products

DOI

ISSN

0163-3864

Publication Date

March 1, 1996

Volume

59

Issue

3

Start / End Page

224 / 231

Related Subject Headings

  • Medicinal & Biomolecular Chemistry
  • 4208 Traditional, complementary and integrative medicine
  • 11 Medical and Health Sciences
  • 06 Biological Sciences
  • 03 Chemical Sciences