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Preparation and characterization of a new artemisinin-derived dimer

Publication ,  Journal Article
Galal, AM; Ahmad, MS; El-Feraly, FS; McPhail, AT
Published in: Journal of Natural Products
October 1, 1996

A new dimer (1) that is likely to be a reduction metabolite of arteether (2), the potent antimalarial agent, was prepared from deoxydihydroartemisinin (3). The identity of 1 was established from spectral data and was confirmed by X-ray crystallographic analysis. In addition, the stereochemistry of the related, previously reported dimer (4), is now more clearly defined, based on revising its X-ray crystallographic data.

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Published In

Journal of Natural Products

DOI

ISSN

0163-3864

Publication Date

October 1, 1996

Volume

59

Issue

10

Start / End Page

917 / 920

Related Subject Headings

  • Medicinal & Biomolecular Chemistry
  • 4208 Traditional, complementary and integrative medicine
  • 11 Medical and Health Sciences
  • 06 Biological Sciences
  • 03 Chemical Sciences
 

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Galal, A. M., Ahmad, M. S., El-Feraly, F. S., & McPhail, A. T. (1996). Preparation and characterization of a new artemisinin-derived dimer. Journal of Natural Products, 59(10), 917–920. https://doi.org/10.1021/np960211a
Galal, A. M., M. S. Ahmad, F. S. El-Feraly, and A. T. McPhail. “Preparation and characterization of a new artemisinin-derived dimer.” Journal of Natural Products 59, no. 10 (October 1, 1996): 917–20. https://doi.org/10.1021/np960211a.
Galal AM, Ahmad MS, El-Feraly FS, McPhail AT. Preparation and characterization of a new artemisinin-derived dimer. Journal of Natural Products. 1996 Oct 1;59(10):917–20.
Galal, A. M., et al. “Preparation and characterization of a new artemisinin-derived dimer.” Journal of Natural Products, vol. 59, no. 10, Oct. 1996, pp. 917–20. Scopus, doi:10.1021/np960211a.
Galal AM, Ahmad MS, El-Feraly FS, McPhail AT. Preparation and characterization of a new artemisinin-derived dimer. Journal of Natural Products. 1996 Oct 1;59(10):917–920.
Journal cover image

Published In

Journal of Natural Products

DOI

ISSN

0163-3864

Publication Date

October 1, 1996

Volume

59

Issue

10

Start / End Page

917 / 920

Related Subject Headings

  • Medicinal & Biomolecular Chemistry
  • 4208 Traditional, complementary and integrative medicine
  • 11 Medical and Health Sciences
  • 06 Biological Sciences
  • 03 Chemical Sciences