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Laminar organization of geniculocortical projections in Galago senegalensis and Aotus trivirgatus.

Publication ,  Journal Article
Diamond, IT; Conley, M; Itoh, K; Fitzpatrick, D
Published in: J Comp Neurol
December 22, 1985

The projections of the lateral geniculate nucleus to striate cortex were traced by anterograde and retrograde transport of WGA-HRP in two primates, Galago and Aotus. The goal was to determine the laminar organization of the terminals of individual layers of the lateral geniculate nucleus. The results show that in both species the magnocellular layers project to cortical layer IV alpha, the parvicellular layers project to IV beta, and the intercalated geniculate layers (which term includes layers 4 and 5 in Galago) project to layers III and I. The distribution of terminals in layer III is periodic, which is to say, there are regularly spaced regions of terminals separated by regions devoid of terminals. When the two species are compared to Saimiri, it is clear that the basic organization of the three pathways relaying in the lateral geniculate nucleus is common to all three primates. At the same time, there are some significant species differences. The total pattern of projections in Galago is compressed in comparison to that in the monkey, and this compression seems to be related to the poorer differentiation of cortical layers in the prosimian. For example, layer IIIC is distinct only in the two monkeys and at the same time it is spared from geniculate terminations. Both Galago and Aotus differ from Saimiri in that they lack a projection from the parvicellular geniculate layers to the layer IIIB. These species comparisons are relevant to the questions of the functional significance of the three pathways and the evolution of the primate striate cortex.

Duke Scholars

Published In

J Comp Neurol

DOI

ISSN

0021-9967

Publication Date

December 22, 1985

Volume

242

Issue

4

Start / End Page

584 / 610

Location

United States

Related Subject Headings

  • Wheat Germ Agglutinins
  • Visual Cortex
  • Species Specificity
  • Neurons
  • Neurology & Neurosurgery
  • Neural Pathways
  • Lectins
  • Injections, Intraventricular
  • Horseradish Peroxidase
  • Geniculate Bodies
 

Citation

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Diamond, I. T., Conley, M., Itoh, K., & Fitzpatrick, D. (1985). Laminar organization of geniculocortical projections in Galago senegalensis and Aotus trivirgatus. J Comp Neurol, 242(4), 584–610. https://doi.org/10.1002/cne.902420408
Diamond, I. T., M. Conley, K. Itoh, and D. Fitzpatrick. “Laminar organization of geniculocortical projections in Galago senegalensis and Aotus trivirgatus.J Comp Neurol 242, no. 4 (December 22, 1985): 584–610. https://doi.org/10.1002/cne.902420408.
Diamond IT, Conley M, Itoh K, Fitzpatrick D. Laminar organization of geniculocortical projections in Galago senegalensis and Aotus trivirgatus. J Comp Neurol. 1985 Dec 22;242(4):584–610.
Diamond, I. T., et al. “Laminar organization of geniculocortical projections in Galago senegalensis and Aotus trivirgatus.J Comp Neurol, vol. 242, no. 4, Dec. 1985, pp. 584–610. Pubmed, doi:10.1002/cne.902420408.
Diamond IT, Conley M, Itoh K, Fitzpatrick D. Laminar organization of geniculocortical projections in Galago senegalensis and Aotus trivirgatus. J Comp Neurol. 1985 Dec 22;242(4):584–610.
Journal cover image

Published In

J Comp Neurol

DOI

ISSN

0021-9967

Publication Date

December 22, 1985

Volume

242

Issue

4

Start / End Page

584 / 610

Location

United States

Related Subject Headings

  • Wheat Germ Agglutinins
  • Visual Cortex
  • Species Specificity
  • Neurons
  • Neurology & Neurosurgery
  • Neural Pathways
  • Lectins
  • Injections, Intraventricular
  • Horseradish Peroxidase
  • Geniculate Bodies