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Complementary nature of radiotracer parathyroid imaging and intraoperative parathyroid hormone assays in the surgical management of primary hyperparathyroid disease: case report and review.

Publication ,  Journal Article
Wilkinson, RH; Leight, GS; Garner, SC; Borges-Neto, S
Published in: Clin Nucl Med
March 2000

PURPOSE: This article illustrates the complementary nature of preoperative radionuclide parathyroid imaging and intraoperative rapid parathyroid hormone (PTH) assays in primary hyperparathyroid disease. The authors review the literature on these procedures and compare this protocol and its cost-effectiveness with those of the classic four-gland exploration. MATERIALS AND METHODS: Preoperative parathyroid imaging with Tc-99m MIBI and intraoperative rapid PTH assays were performed at the time of neck exploration. RESULTS: One of two parathyroid adenomas seen on radionuclide images would have been missed if the authors had relied solely on the initial decrease in PTH assay value to a normal level. CONCLUSIONS: Tc-99m MIBI imaging and intraoperative rapid PTH assays are complementary; when used together, they lessen the likelihood that abnormal parathyroid glands will be overlooked. This experience and that of others suggest these combined procedures are cost-effective.

Duke Scholars

Published In

Clin Nucl Med

DOI

ISSN

0363-9762

Publication Date

March 2000

Volume

25

Issue

3

Start / End Page

173 / 178

Location

United States

Related Subject Headings

  • Technetium Tc 99m Sestamibi
  • Radiopharmaceuticals
  • Radionuclide Imaging
  • Parathyroidectomy
  • Parathyroid Neoplasms
  • Parathyroid Hormone
  • Parathyroid Glands
  • Nuclear Medicine & Medical Imaging
  • Male
  • Intraoperative Period
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Wilkinson, R. H., Leight, G. S., Garner, S. C., & Borges-Neto, S. (2000). Complementary nature of radiotracer parathyroid imaging and intraoperative parathyroid hormone assays in the surgical management of primary hyperparathyroid disease: case report and review. Clin Nucl Med, 25(3), 173–178. https://doi.org/10.1097/00003072-200003000-00002
Wilkinson, R. H., G. S. Leight, S. C. Garner, and S. Borges-Neto. “Complementary nature of radiotracer parathyroid imaging and intraoperative parathyroid hormone assays in the surgical management of primary hyperparathyroid disease: case report and review.Clin Nucl Med 25, no. 3 (March 2000): 173–78. https://doi.org/10.1097/00003072-200003000-00002.
Wilkinson, R. H., et al. “Complementary nature of radiotracer parathyroid imaging and intraoperative parathyroid hormone assays in the surgical management of primary hyperparathyroid disease: case report and review.Clin Nucl Med, vol. 25, no. 3, Mar. 2000, pp. 173–78. Pubmed, doi:10.1097/00003072-200003000-00002.

Published In

Clin Nucl Med

DOI

ISSN

0363-9762

Publication Date

March 2000

Volume

25

Issue

3

Start / End Page

173 / 178

Location

United States

Related Subject Headings

  • Technetium Tc 99m Sestamibi
  • Radiopharmaceuticals
  • Radionuclide Imaging
  • Parathyroidectomy
  • Parathyroid Neoplasms
  • Parathyroid Hormone
  • Parathyroid Glands
  • Nuclear Medicine & Medical Imaging
  • Male
  • Intraoperative Period