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Breast cancer in older patients.

Publication ,  Journal Article
Kimmick, G; Muss, HB
Published in: Semin Oncol
April 2004

Breast cancer is a common problem and a major health concern in our growing geriatric population. Older breast cancer patients are at risk for less than standard management, the appropriateness of which is difficult to discern. Breast tumors tend to have less aggressive characteristics. In addition, planning therapy is not always straightforward because older patients may present with comorbid illnesses and frailty that limit therapeutic choices. Standard management approaches should always be considered first. Here, we outline some data supporting standard treatment for breast cancer in older women. We also describe other options that can be considered in circumstances when the standard treatment is not possible. For instance, primary treatment with tamoxifen or an aromatase inhibitor is justifiable in a patient who is unfit for surgery and axillary dissection may be unnecessary in a patient who is obviously unfit for adjuvant chemotherapy. Adjuvant therapies should be considered, weighing risks and benefits for each patient, though the threshold for using chemotherapy may be higher. The goals in treating metastatic breast cancer in an older patient are not different than for younger patients.

Duke Scholars

Published In

Semin Oncol

DOI

ISSN

0093-7754

Publication Date

April 2004

Volume

31

Issue

2

Start / End Page

234 / 248

Location

United States

Related Subject Headings

  • Oncology & Carcinogenesis
  • Life Expectancy
  • Humans
  • Female
  • Comorbidity
  • Combined Modality Therapy
  • Breast Neoplasms
  • Aged
  • 3211 Oncology and carcinogenesis
  • 1112 Oncology and Carcinogenesis
 

Citation

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Kimmick, G., & Muss, H. B. (2004). Breast cancer in older patients. Semin Oncol, 31(2), 234–248. https://doi.org/10.1053/j.seminoncol.2003.12.033
Kimmick, Gretchen, and Hyman B. Muss. “Breast cancer in older patients.Semin Oncol 31, no. 2 (April 2004): 234–48. https://doi.org/10.1053/j.seminoncol.2003.12.033.
Kimmick G, Muss HB. Breast cancer in older patients. Semin Oncol. 2004 Apr;31(2):234–48.
Kimmick, Gretchen, and Hyman B. Muss. “Breast cancer in older patients.Semin Oncol, vol. 31, no. 2, Apr. 2004, pp. 234–48. Pubmed, doi:10.1053/j.seminoncol.2003.12.033.
Kimmick G, Muss HB. Breast cancer in older patients. Semin Oncol. 2004 Apr;31(2):234–248.
Journal cover image

Published In

Semin Oncol

DOI

ISSN

0093-7754

Publication Date

April 2004

Volume

31

Issue

2

Start / End Page

234 / 248

Location

United States

Related Subject Headings

  • Oncology & Carcinogenesis
  • Life Expectancy
  • Humans
  • Female
  • Comorbidity
  • Combined Modality Therapy
  • Breast Neoplasms
  • Aged
  • 3211 Oncology and carcinogenesis
  • 1112 Oncology and Carcinogenesis