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An overview of imaging techniques and physical aspects of treatment planning in radioimmunotherapy.

Publication ,  Journal Article
Leichner, PK; Koral, KF; Jaszczak, RJ; Green, AJ; Chen, GT; Roeske, JC
Published in: Med Phys
1993

Planar and tomographic imaging techniques and methods of treatment planning in clinical radioimmunotherapy are reviewed. In clinical trials, the data needed for dosimetry and treatment planning are, in most cases, obtained from noninvasive imaging procedures. The required data include tumor and normal organ volumes, the activity of radiolabeled antibodies taken up in these volumes, and the pharmacokinetics of the administered activity of radiolabeled antibodies. Therefore, the topics addressed in this review include: (1) Volume determination of tumors and normal organs from x-ray-computed tomography and magnetic resonance imaging, (2) quantitation of the activity of radiolabeled antibodies in tumors and normal organs from planar gamma camera views, (3) quantitative single-photon emission computed tomography and positron emission tomography, (4) correlative image analysis, and (5) treatment planning in clinical radioimmunotherapy.

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Published In

Med Phys

DOI

ISSN

0094-2405

Publication Date

1993

Volume

20

Issue

2 Pt 2

Start / End Page

569 / 577

Location

United States

Related Subject Headings

  • Tomography, X-Ray Computed
  • Tomography, Emission-Computed, Single-Photon
  • Tomography, Emission-Computed
  • Radioimmunotherapy
  • Nuclear Medicine & Medical Imaging
  • Neoplasms
  • Magnetic Resonance Imaging
  • Image Processing, Computer-Assisted
  • Humans
  • 5105 Medical and biological physics
 

Citation

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Leichner, P. K., Koral, K. F., Jaszczak, R. J., Green, A. J., Chen, G. T., & Roeske, J. C. (1993). An overview of imaging techniques and physical aspects of treatment planning in radioimmunotherapy. Med Phys, 20(2 Pt 2), 569–577. https://doi.org/10.1118/1.597051
Leichner, P. K., K. F. Koral, R. J. Jaszczak, A. J. Green, G. T. Chen, and J. C. Roeske. “An overview of imaging techniques and physical aspects of treatment planning in radioimmunotherapy.Med Phys 20, no. 2 Pt 2 (1993): 569–77. https://doi.org/10.1118/1.597051.
Leichner PK, Koral KF, Jaszczak RJ, Green AJ, Chen GT, Roeske JC. An overview of imaging techniques and physical aspects of treatment planning in radioimmunotherapy. Med Phys. 1993;20(2 Pt 2):569–77.
Leichner, P. K., et al. “An overview of imaging techniques and physical aspects of treatment planning in radioimmunotherapy.Med Phys, vol. 20, no. 2 Pt 2, 1993, pp. 569–77. Pubmed, doi:10.1118/1.597051.
Leichner PK, Koral KF, Jaszczak RJ, Green AJ, Chen GT, Roeske JC. An overview of imaging techniques and physical aspects of treatment planning in radioimmunotherapy. Med Phys. 1993;20(2 Pt 2):569–577.

Published In

Med Phys

DOI

ISSN

0094-2405

Publication Date

1993

Volume

20

Issue

2 Pt 2

Start / End Page

569 / 577

Location

United States

Related Subject Headings

  • Tomography, X-Ray Computed
  • Tomography, Emission-Computed, Single-Photon
  • Tomography, Emission-Computed
  • Radioimmunotherapy
  • Nuclear Medicine & Medical Imaging
  • Neoplasms
  • Magnetic Resonance Imaging
  • Image Processing, Computer-Assisted
  • Humans
  • 5105 Medical and biological physics