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Transtympanic steroids for treatment of sudden hearing loss.

Publication ,  Journal Article
Gianoli, GJ; Li, JC
Published in: Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
September 2001

OBJECTIVES: To determine whether transtympanic steroid administration may be an effective treatment for sudden onset sensorineural hearing loss (SSNHL) in patients for whom systemic steroid treatment has failed or who were not candidates for systemic steroids. METHODS: The standard medical regimen for SSNHL usually involves systemic steroid therapy. Unfortunately, some patients do not respond successfully to or are poorly tolerant of systemic steroids. Transtympanic administration of steroids has been suggested as an alternative to systemic therapy. A prospective study was designed to evaluate the hearing outcomes in SSNHL patients treated with transtympanic steroids. Patients received transtympanic steroids if oral steroids had failed to work or if they were not able to tolerate oral steroids. Transtympanic steroids were administered through a ventilation tube placed with the patient under local anesthesia. Steroid administration was performed on 4 separate occasions over the course of 10 to 14 days. Hearing was assessed immediately before therapy and within 1 to 2 weeks after therapy. RESULTS: Hearing improvement was documented in 10 of 23 patients (44%) who underwent transtympanic steroid administration. This represents a 44% hearing salvage in patients for whom steroid treatment would otherwise have been considered a failure. CONCLUSION: Transtympanic steroid therapy may be an alternative treatment for patients with SSNHL for whom systemic steroid therapy had failed or who could not tolerate systemic steroid therapy.

Duke Scholars

Published In

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery

ISSN

0194-5998

Publication Date

September 2001

Volume

125

Issue

3

Start / End Page

142 / 146

Location

united states

Related Subject Headings

  • Otorhinolaryngology
  • 1103 Clinical Sciences
 

Citation

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Chicago
ICMJE
MLA
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Gianoli, G. J., & Li, J. C. (2001). Transtympanic steroids for treatment of sudden hearing loss. Otolaryngology--Head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery, 125(3), 142–146.
Gianoli, G. J., and J. C. Li. “Transtympanic steroids for treatment of sudden hearing loss.Otolaryngology--Head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery 125, no. 3 (September 2001): 142–46.
Gianoli GJ, Li JC. Transtympanic steroids for treatment of sudden hearing loss. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery. 2001 Sep;125(3):142–6.
Gianoli, G. J., and J. C. Li. “Transtympanic steroids for treatment of sudden hearing loss.Otolaryngology--Head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery, vol. 125, no. 3, Sept. 2001, pp. 142–46.
Gianoli GJ, Li JC. Transtympanic steroids for treatment of sudden hearing loss. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery. 2001 Sep;125(3):142–146.
Journal cover image

Published In

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery

ISSN

0194-5998

Publication Date

September 2001

Volume

125

Issue

3

Start / End Page

142 / 146

Location

united states

Related Subject Headings

  • Otorhinolaryngology
  • 1103 Clinical Sciences