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The effects of transtympanic micropressure treatment in people with unilateral Meniere's disease.

Publication ,  Journal Article
Gates, GA; Green, JD; Tucci, DL; Telian, SA
Published in: Arch Otolaryngol Head Neck Surg
June 2004

OBJECTIVE: To evaluate the efficacy of a portable low-intensity alternating pressure generator, the Meniett device, in controlling the symptoms of Ménière's disease. DESIGN: A randomized, placebo-controlled, double-blind, multicenter clinical trial of 4 months' duration. SETTING: Four study sites: 3 academic medical centers and 1 private practice. PATIENTS: Sixty-seven people aged 33 to 71 years with established, active, unilateral cochleovestibular Ménière's disease randomly assigned to a treatment or control group. Five cases were excluded (2 dropouts, 3 protocol violations), leaving 62 evaluable cases. INTERVENTION: The Meniett device was self-administered 3 times daily. The placebo Meniett device was identical but exerted no pressure. All participants had a tympanostomy tube inserted in the affected ear. MAIN OUTCOME MEASURES: Participants rated vertigo and activity each day on a symptom report card. Hearing tests, electrocochleography, and questionnaires were completed at baseline, 2 months, and 4 months. RESULTS: The treatment group experienced significantly less severe vertigo, fewer days with definitive vertigo, and fewer days lost from work (sick days) during the follow-up period than did the control group. Hearing and electrocochleographic results did not differ between the groups. Outcomes did not differ by age, gender, laterality, or duration of symptoms. Outcomes were affected by vestibular loss and baseline level of vertigo. The tympanostomy tube had no short-term effect on vertigo symptoms. There were no complications from using the Meniett device. CONCLUSION: The Meniett device is a minimally invasive, safe, and efficacious intermediate treatment for people with substantial vertigo uncontrolled by medical therapy.

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Published In

Arch Otolaryngol Head Neck Surg

DOI

ISSN

0886-4470

Publication Date

June 2004

Volume

130

Issue

6

Start / End Page

718 / 725

Location

United States

Related Subject Headings

  • Vertigo
  • Treatment Outcome
  • Sick Leave
  • Prospective Studies
  • Pressure
  • Physical Therapy Modalities
  • Otorhinolaryngology
  • Middle Ear Ventilation
  • Middle Aged
  • Meniere Disease
 

Citation

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ICMJE
MLA
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Gates, G. A., Green, J. D., Tucci, D. L., & Telian, S. A. (2004). The effects of transtympanic micropressure treatment in people with unilateral Meniere's disease. Arch Otolaryngol Head Neck Surg, 130(6), 718–725. https://doi.org/10.1001/archotol.130.6.718
Gates, George A., J Douglas Green, Debara L. Tucci, and Steven A. Telian. “The effects of transtympanic micropressure treatment in people with unilateral Meniere's disease.Arch Otolaryngol Head Neck Surg 130, no. 6 (June 2004): 718–25. https://doi.org/10.1001/archotol.130.6.718.
Gates GA, Green JD, Tucci DL, Telian SA. The effects of transtympanic micropressure treatment in people with unilateral Meniere's disease. Arch Otolaryngol Head Neck Surg. 2004 Jun;130(6):718–25.
Gates, George A., et al. “The effects of transtympanic micropressure treatment in people with unilateral Meniere's disease.Arch Otolaryngol Head Neck Surg, vol. 130, no. 6, June 2004, pp. 718–25. Pubmed, doi:10.1001/archotol.130.6.718.
Gates GA, Green JD, Tucci DL, Telian SA. The effects of transtympanic micropressure treatment in people with unilateral Meniere's disease. Arch Otolaryngol Head Neck Surg. 2004 Jun;130(6):718–725.

Published In

Arch Otolaryngol Head Neck Surg

DOI

ISSN

0886-4470

Publication Date

June 2004

Volume

130

Issue

6

Start / End Page

718 / 725

Location

United States

Related Subject Headings

  • Vertigo
  • Treatment Outcome
  • Sick Leave
  • Prospective Studies
  • Pressure
  • Physical Therapy Modalities
  • Otorhinolaryngology
  • Middle Ear Ventilation
  • Middle Aged
  • Meniere Disease