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Phase II study of etoposide for carcinoma of the prostate.

Publication ,  Journal Article
Walther, PJ; Williams, SD; Troner, M; Greco, FA; Birch, R; Einhorn, LH
Published in: Cancer Treat Rep
June 1986

The treatment of prostate carcinoma with the epipodophyllotoxin derivative etoposide was studied in a multi-institutional phase II trial. An iv dose schedule of 130 mg/m2 daily for 3 days every 3 weeks was utilized. A total of 36 patients were evaluable; the observed total response was 3%. Moderate toxicity (predominantly myelosuppression) was seen utilizing this treatment schedule. It is concluded that etoposide possesses little single-agent therapeutic activity for prostate carcinoma.

Duke Scholars

Published In

Cancer Treat Rep

ISSN

0361-5960

Publication Date

June 1986

Volume

70

Issue

6

Start / End Page

771 / 772

Location

United States

Related Subject Headings

  • Prostatic Neoplasms
  • Podophyllotoxin
  • Male
  • Humans
  • Hematologic Diseases
  • Etoposide
  • Drug Evaluation
  • Clinical Trials as Topic
  • Blood Cell Count
 

Citation

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MLA
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Walther, P. J., Williams, S. D., Troner, M., Greco, F. A., Birch, R., & Einhorn, L. H. (1986). Phase II study of etoposide for carcinoma of the prostate. Cancer Treat Rep, 70(6), 771–772.
Walther, P. J., S. D. Williams, M. Troner, F. A. Greco, R. Birch, and L. H. Einhorn. “Phase II study of etoposide for carcinoma of the prostate.Cancer Treat Rep 70, no. 6 (June 1986): 771–72.
Walther PJ, Williams SD, Troner M, Greco FA, Birch R, Einhorn LH. Phase II study of etoposide for carcinoma of the prostate. Cancer Treat Rep. 1986 Jun;70(6):771–2.
Walther, P. J., et al. “Phase II study of etoposide for carcinoma of the prostate.Cancer Treat Rep, vol. 70, no. 6, June 1986, pp. 771–72.
Walther PJ, Williams SD, Troner M, Greco FA, Birch R, Einhorn LH. Phase II study of etoposide for carcinoma of the prostate. Cancer Treat Rep. 1986 Jun;70(6):771–772.

Published In

Cancer Treat Rep

ISSN

0361-5960

Publication Date

June 1986

Volume

70

Issue

6

Start / End Page

771 / 772

Location

United States

Related Subject Headings

  • Prostatic Neoplasms
  • Podophyllotoxin
  • Male
  • Humans
  • Hematologic Diseases
  • Etoposide
  • Drug Evaluation
  • Clinical Trials as Topic
  • Blood Cell Count