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Detection of metastatic tumors in nude mice: brief communication.

Publication ,  Journal Article
Graham, SD; mickey, DD; Paulson, DF
Published in: J Natl Cancer Inst
March 1978

Homozygous nude (nu/nu) mice were inoculated ip with either highly malignant human bladder transitional cell carcinoma or human prostate adenocarcinoma. These animals were subsequently given injections of normal human T-lymphocytes to restore the known T-lymphocyte deficiency present in homozygous nude mice. Metastatic spread of the prostate and bladder carcinomas was evident in mice given human T-lymphocytes. Although tumor growth was observed at the sites of tumor inoculation, no tumor spread was observed in mice not receiving T-lymphocytes.

Duke Scholars

Published In

J Natl Cancer Inst

DOI

ISSN

0027-8874

Publication Date

March 1978

Volume

60

Issue

3

Start / End Page

715 / 716

Location

United States

Related Subject Headings

  • Urinary Bladder Neoplasms
  • Transplantation, Heterologous
  • T-Lymphocytes
  • Prostatic Neoplasms
  • Oncology & Carcinogenesis
  • Neoplasms, Experimental
  • Neoplasm Transplantation
  • Neoplasm Metastasis
  • Mice, Nude
  • Mice
 

Citation

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MLA
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Graham, S. D., mickey, D. D., & Paulson, D. F. (1978). Detection of metastatic tumors in nude mice: brief communication. J Natl Cancer Inst, 60(3), 715–716. https://doi.org/10.1093/jnci/60.3.715
Graham, S. D., D. D. mickey, and D. F. Paulson. “Detection of metastatic tumors in nude mice: brief communication.J Natl Cancer Inst 60, no. 3 (March 1978): 715–16. https://doi.org/10.1093/jnci/60.3.715.
Graham SD, mickey DD, Paulson DF. Detection of metastatic tumors in nude mice: brief communication. J Natl Cancer Inst. 1978 Mar;60(3):715–6.
Graham, S. D., et al. “Detection of metastatic tumors in nude mice: brief communication.J Natl Cancer Inst, vol. 60, no. 3, Mar. 1978, pp. 715–16. Pubmed, doi:10.1093/jnci/60.3.715.
Graham SD, mickey DD, Paulson DF. Detection of metastatic tumors in nude mice: brief communication. J Natl Cancer Inst. 1978 Mar;60(3):715–716.
Journal cover image

Published In

J Natl Cancer Inst

DOI

ISSN

0027-8874

Publication Date

March 1978

Volume

60

Issue

3

Start / End Page

715 / 716

Location

United States

Related Subject Headings

  • Urinary Bladder Neoplasms
  • Transplantation, Heterologous
  • T-Lymphocytes
  • Prostatic Neoplasms
  • Oncology & Carcinogenesis
  • Neoplasms, Experimental
  • Neoplasm Transplantation
  • Neoplasm Metastasis
  • Mice, Nude
  • Mice