The effects of castration on adrenal testosterone secretion in men with prostatic carcinoma.
Publication
, Journal Article
Sanford, EJ; Paulson, DF; Rohner, TJ; Santen, RJ; Bardin, CW
Published in: J Urol
December 1977
Selective adrenal vein catheterization was done on intact and castrated men with prostatic carcinoma. Adrenal to peripheral venous testosterone gradients were observed in all patients, indicating adrenal production of this hormone. No compensatory adrenal production of testosterone was noted during a 17-month period after orchiectomy. The data suggest that the human adrenal in castrates produces testosterone, which may explain why adrenal ablation can offer palliation in some patients with prostatic carcinoma.
Duke Scholars
Published In
J Urol
DOI
ISSN
0022-5347
Publication Date
December 1977
Volume
118
Issue
6
Start / End Page
1019 / 1021
Location
United States
Related Subject Headings
- Urology & Nephrology
- Testosterone
- Prostatic Neoplasms
- Palliative Care
- Male
- Humans
- Catheterization
- Castration
- Adrenal Glands
- 3202 Clinical sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Sanford, E. J., Paulson, D. F., Rohner, T. J., Santen, R. J., & Bardin, C. W. (1977). The effects of castration on adrenal testosterone secretion in men with prostatic carcinoma. J Urol, 118(6), 1019–1021. https://doi.org/10.1016/s0022-5347(17)58283-x
Sanford, E. J., D. F. Paulson, T. J. Rohner, R. J. Santen, and C. W. Bardin. “The effects of castration on adrenal testosterone secretion in men with prostatic carcinoma.” J Urol 118, no. 6 (December 1977): 1019–21. https://doi.org/10.1016/s0022-5347(17)58283-x.
Sanford EJ, Paulson DF, Rohner TJ, Santen RJ, Bardin CW. The effects of castration on adrenal testosterone secretion in men with prostatic carcinoma. J Urol. 1977 Dec;118(6):1019–21.
Sanford, E. J., et al. “The effects of castration on adrenal testosterone secretion in men with prostatic carcinoma.” J Urol, vol. 118, no. 6, Dec. 1977, pp. 1019–21. Pubmed, doi:10.1016/s0022-5347(17)58283-x.
Sanford EJ, Paulson DF, Rohner TJ, Santen RJ, Bardin CW. The effects of castration on adrenal testosterone secretion in men with prostatic carcinoma. J Urol. 1977 Dec;118(6):1019–1021.
Published In
J Urol
DOI
ISSN
0022-5347
Publication Date
December 1977
Volume
118
Issue
6
Start / End Page
1019 / 1021
Location
United States
Related Subject Headings
- Urology & Nephrology
- Testosterone
- Prostatic Neoplasms
- Palliative Care
- Male
- Humans
- Catheterization
- Castration
- Adrenal Glands
- 3202 Clinical sciences