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1,10-Phenanthroline reversibility inhibits proliferation of two human prostate carcinoma cell lines (PC-3 and DU145).

Publication ,  Journal Article
Ware, JL; Paulson, DF; Webb, KS
Published in: Biochem Biophys Res Commun
October 30, 1984

The metal chelator 1,10-phenanthroline reversibly inhibits proliferation of two human prostate carcinoma cell lines, PC-3 and DU145. Inhibition is dose-dependent, and persists for several days after removal of the chelator. The ability to induce reversible quiescence in human prostate carcinoma cells in vitro may facilitate the study of their growth cycle biochemistry.

Duke Scholars

Published In

Biochem Biophys Res Commun

DOI

ISSN

0006-291X

Publication Date

October 30, 1984

Volume

124

Issue

2

Start / End Page

538 / 543

Location

United States

Related Subject Headings

  • Thymidine
  • Prostatic Neoplasms
  • Phenanthrolines
  • Male
  • Kinetics
  • Humans
  • Epitopes
  • DNA Replication
  • Cell Line
  • Cell Division
 

Citation

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ICMJE
MLA
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Ware, J. L., Paulson, D. F., & Webb, K. S. (1984). 1,10-Phenanthroline reversibility inhibits proliferation of two human prostate carcinoma cell lines (PC-3 and DU145). Biochem Biophys Res Commun, 124(2), 538–543. https://doi.org/10.1016/0006-291x(84)91587-0
Ware, J. L., D. F. Paulson, and K. S. Webb. “1,10-Phenanthroline reversibility inhibits proliferation of two human prostate carcinoma cell lines (PC-3 and DU145).Biochem Biophys Res Commun 124, no. 2 (October 30, 1984): 538–43. https://doi.org/10.1016/0006-291x(84)91587-0.
Ware JL, Paulson DF, Webb KS. 1,10-Phenanthroline reversibility inhibits proliferation of two human prostate carcinoma cell lines (PC-3 and DU145). Biochem Biophys Res Commun. 1984 Oct 30;124(2):538–43.
Ware, J. L., et al. “1,10-Phenanthroline reversibility inhibits proliferation of two human prostate carcinoma cell lines (PC-3 and DU145).Biochem Biophys Res Commun, vol. 124, no. 2, Oct. 1984, pp. 538–43. Pubmed, doi:10.1016/0006-291x(84)91587-0.
Ware JL, Paulson DF, Webb KS. 1,10-Phenanthroline reversibility inhibits proliferation of two human prostate carcinoma cell lines (PC-3 and DU145). Biochem Biophys Res Commun. 1984 Oct 30;124(2):538–543.
Journal cover image

Published In

Biochem Biophys Res Commun

DOI

ISSN

0006-291X

Publication Date

October 30, 1984

Volume

124

Issue

2

Start / End Page

538 / 543

Location

United States

Related Subject Headings

  • Thymidine
  • Prostatic Neoplasms
  • Phenanthrolines
  • Male
  • Kinetics
  • Humans
  • Epitopes
  • DNA Replication
  • Cell Line
  • Cell Division