Creutzfeldt-Jakob disease in a pregnant woman with an implanted dura mater graft.
Publication
, Journal Article
Lane, KL; Brown, P; Howell, DN; Crain, BJ; Hulette, CM; Burger, PC; DeArmond, SJ
Published in: Neurosurgery
April 1994
A 28-year-old woman with prior neurosurgery involving the placement of a cadaveric dural graft developed a rapidly progressive neurodegenerative disorder with prominent cerebellar dysfunction that was proven at autopsy to be Creutzfeldt-Jakob disease. She represents the second American to develop Creutzfeldt-Jakob disease in association with a dural graft. The unusual features of the case include the patient's initial clinical presentation with cerebellar ataxia in the absence of dementia, the widespread presence of kuru-type amyloid plaques on a histological examination of the brain, the development of clinical symptoms during pregnancy, and the subsequent delivery of a child who remains healthy at the age of 3 years.
Duke Scholars
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Published In
Neurosurgery
DOI
ISSN
0148-396X
Publication Date
April 1994
Volume
34
Issue
4
Start / End Page
737 / 739
Location
United States
Related Subject Headings
- Pregnancy Complications, Infectious
- Pregnancy
- Postoperative Complications
- Neurology & Neurosurgery
- Neurologic Examination
- Nerve Degeneration
- Male
- Infant, Newborn
- Humans
- Female
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Lane, K. L., Brown, P., Howell, D. N., Crain, B. J., Hulette, C. M., Burger, P. C., & DeArmond, S. J. (1994). Creutzfeldt-Jakob disease in a pregnant woman with an implanted dura mater graft. Neurosurgery, 34(4), 737–739. https://doi.org/10.1227/00006123-199404000-00026
Lane, K. L., P. Brown, D. N. Howell, B. J. Crain, C. M. Hulette, P. C. Burger, and S. J. DeArmond. “Creutzfeldt-Jakob disease in a pregnant woman with an implanted dura mater graft.” Neurosurgery 34, no. 4 (April 1994): 737–39. https://doi.org/10.1227/00006123-199404000-00026.
Lane KL, Brown P, Howell DN, Crain BJ, Hulette CM, Burger PC, et al. Creutzfeldt-Jakob disease in a pregnant woman with an implanted dura mater graft. Neurosurgery. 1994 Apr;34(4):737–9.
Lane, K. L., et al. “Creutzfeldt-Jakob disease in a pregnant woman with an implanted dura mater graft.” Neurosurgery, vol. 34, no. 4, Apr. 1994, pp. 737–39. Pubmed, doi:10.1227/00006123-199404000-00026.
Lane KL, Brown P, Howell DN, Crain BJ, Hulette CM, Burger PC, DeArmond SJ. Creutzfeldt-Jakob disease in a pregnant woman with an implanted dura mater graft. Neurosurgery. 1994 Apr;34(4):737–739.
Published In
Neurosurgery
DOI
ISSN
0148-396X
Publication Date
April 1994
Volume
34
Issue
4
Start / End Page
737 / 739
Location
United States
Related Subject Headings
- Pregnancy Complications, Infectious
- Pregnancy
- Postoperative Complications
- Neurology & Neurosurgery
- Neurologic Examination
- Nerve Degeneration
- Male
- Infant, Newborn
- Humans
- Female