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Creutzfeldt-Jakob disease in a pregnant woman with an implanted dura mater graft.

Publication ,  Journal Article
Lane, KL; Brown, P; Howell, DN; Crain, BJ; Hulette, CM; Burger, PC; DeArmond, SJ
Published in: Neurosurgery
April 1994

A 28-year-old woman with prior neurosurgery involving the placement of a cadaveric dural graft developed a rapidly progressive neurodegenerative disorder with prominent cerebellar dysfunction that was proven at autopsy to be Creutzfeldt-Jakob disease. She represents the second American to develop Creutzfeldt-Jakob disease in association with a dural graft. The unusual features of the case include the patient's initial clinical presentation with cerebellar ataxia in the absence of dementia, the widespread presence of kuru-type amyloid plaques on a histological examination of the brain, the development of clinical symptoms during pregnancy, and the subsequent delivery of a child who remains healthy at the age of 3 years.

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Published In

Neurosurgery

DOI

ISSN

0148-396X

Publication Date

April 1994

Volume

34

Issue

4

Start / End Page

737 / 739

Location

United States

Related Subject Headings

  • Pregnancy Complications, Infectious
  • Pregnancy
  • Postoperative Complications
  • Neurology & Neurosurgery
  • Neurologic Examination
  • Nerve Degeneration
  • Male
  • Infant, Newborn
  • Humans
  • Female
 

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Lane, K. L., Brown, P., Howell, D. N., Crain, B. J., Hulette, C. M., Burger, P. C., & DeArmond, S. J. (1994). Creutzfeldt-Jakob disease in a pregnant woman with an implanted dura mater graft. Neurosurgery, 34(4), 737–739. https://doi.org/10.1227/00006123-199404000-00026
Lane, K. L., P. Brown, D. N. Howell, B. J. Crain, C. M. Hulette, P. C. Burger, and S. J. DeArmond. “Creutzfeldt-Jakob disease in a pregnant woman with an implanted dura mater graft.Neurosurgery 34, no. 4 (April 1994): 737–39. https://doi.org/10.1227/00006123-199404000-00026.
Lane KL, Brown P, Howell DN, Crain BJ, Hulette CM, Burger PC, et al. Creutzfeldt-Jakob disease in a pregnant woman with an implanted dura mater graft. Neurosurgery. 1994 Apr;34(4):737–9.
Lane, K. L., et al. “Creutzfeldt-Jakob disease in a pregnant woman with an implanted dura mater graft.Neurosurgery, vol. 34, no. 4, Apr. 1994, pp. 737–39. Pubmed, doi:10.1227/00006123-199404000-00026.
Lane KL, Brown P, Howell DN, Crain BJ, Hulette CM, Burger PC, DeArmond SJ. Creutzfeldt-Jakob disease in a pregnant woman with an implanted dura mater graft. Neurosurgery. 1994 Apr;34(4):737–739.
Journal cover image

Published In

Neurosurgery

DOI

ISSN

0148-396X

Publication Date

April 1994

Volume

34

Issue

4

Start / End Page

737 / 739

Location

United States

Related Subject Headings

  • Pregnancy Complications, Infectious
  • Pregnancy
  • Postoperative Complications
  • Neurology & Neurosurgery
  • Neurologic Examination
  • Nerve Degeneration
  • Male
  • Infant, Newborn
  • Humans
  • Female