The quantity and quality of worldwide new drug introductions, 1982-2003.
Publication
, Journal Article
Grabowski, HG; Wang, YR
Published in: Health affairs (Project Hope)
March 2006
We examined trends in the introduction of new chemical entities (NCEs) worldwide from 1982 through 2003. Although annual introductions of NCEs decreased over time, introductions of high-quality NCEs (that is, global and first-in-class NCEs) increased moderately. Both biotech and orphan products enjoyed tremendous growth, especially for cancer treatment. Country-level analyses for 1993-2003 indicate that U.S. firms overtook their European counterparts in innovative performance or the introduction of first-in-class, biotech, and orphan products. The United States also became the leading market for first launch.
Duke Scholars
Altmetric Attention Stats
Dimensions Citation Stats
Published In
Health affairs (Project Hope)
DOI
EISSN
1544-5208
ISSN
0278-2715
Publication Date
March 2006
Volume
25
Issue
2
Start / End Page
452 / 460
Related Subject Headings
- United States
- Orphan Drug Production
- Investigational New Drug Application
- Humans
- Health Policy & Services
- Global Health
- Europe
- Drugs, Investigational
- Drug Industry
- Biotechnology
Citation
APA
Chicago
ICMJE
MLA
NLM
Grabowski, H. G., & Wang, Y. R. (2006). The quantity and quality of worldwide new drug introductions, 1982-2003. Health Affairs (Project Hope), 25(2), 452–460. https://doi.org/10.1377/hlthaff.25.2.452
Grabowski, Henry G., and Y Richard Wang. “The quantity and quality of worldwide new drug introductions, 1982-2003.” Health Affairs (Project Hope) 25, no. 2 (March 2006): 452–60. https://doi.org/10.1377/hlthaff.25.2.452.
Grabowski HG, Wang YR. The quantity and quality of worldwide new drug introductions, 1982-2003. Health affairs (Project Hope). 2006 Mar;25(2):452–60.
Grabowski, Henry G., and Y. Richard Wang. “The quantity and quality of worldwide new drug introductions, 1982-2003.” Health Affairs (Project Hope), vol. 25, no. 2, Mar. 2006, pp. 452–60. Epmc, doi:10.1377/hlthaff.25.2.452.
Grabowski HG, Wang YR. The quantity and quality of worldwide new drug introductions, 1982-2003. Health affairs (Project Hope). 2006 Mar;25(2):452–460.
Published In
Health affairs (Project Hope)
DOI
EISSN
1544-5208
ISSN
0278-2715
Publication Date
March 2006
Volume
25
Issue
2
Start / End Page
452 / 460
Related Subject Headings
- United States
- Orphan Drug Production
- Investigational New Drug Application
- Humans
- Health Policy & Services
- Global Health
- Europe
- Drugs, Investigational
- Drug Industry
- Biotechnology