PTPRC (CD45) is not associated with the development of multiple sclerosis in U.S. patients.
Publication
, Journal Article
Barcellos, LF; Caillier, S; Dragone, L; Elder, M; Vittinghoff, E; Bucher, P; Lincoln, RR; Pericak-Vance, M; Haines, JL; Weiss, A; Hauser, SL ...
Published in: Nat Genet
September 2001
A C-->G nucleotide transition in exon 4 of PTPRC (encoding protein-tyrosine phosphatase receptor-type C, also known as CD45) was recently reported to be genetically associated with the development of multiple sclerosis (MS). We performed an extensive evaluation of this polymorphism using large family-based and case-control comparisons. Overall, we observed no evidence of genetic association between the PTPRC polymorphism and MS susceptibility or disease course.
Duke Scholars
Published In
Nat Genet
DOI
ISSN
1061-4036
Publication Date
September 2001
Volume
29
Issue
1
Start / End Page
23 / 24
Location
United States
Related Subject Headings
- United States
- Polymorphism, Genetic
- Point Mutation
- Multiple Sclerosis
- Male
- Leukocyte Common Antigens
- Humans
- Female
- Exons
- Developmental Biology
Citation
APA
Chicago
ICMJE
MLA
NLM
Barcellos, L. F., Caillier, S., Dragone, L., Elder, M., Vittinghoff, E., Bucher, P., … Oksenberg, J. R. (2001). PTPRC (CD45) is not associated with the development of multiple sclerosis in U.S. patients. Nat Genet, 29(1), 23–24. https://doi.org/10.1038/ng722
Barcellos, L. F., S. Caillier, L. Dragone, M. Elder, E. Vittinghoff, P. Bucher, R. R. Lincoln, et al. “PTPRC (CD45) is not associated with the development of multiple sclerosis in U.S. patients.” Nat Genet 29, no. 1 (September 2001): 23–24. https://doi.org/10.1038/ng722.
Barcellos LF, Caillier S, Dragone L, Elder M, Vittinghoff E, Bucher P, et al. PTPRC (CD45) is not associated with the development of multiple sclerosis in U.S. patients. Nat Genet. 2001 Sep;29(1):23–4.
Barcellos, L. F., et al. “PTPRC (CD45) is not associated with the development of multiple sclerosis in U.S. patients.” Nat Genet, vol. 29, no. 1, Sept. 2001, pp. 23–24. Pubmed, doi:10.1038/ng722.
Barcellos LF, Caillier S, Dragone L, Elder M, Vittinghoff E, Bucher P, Lincoln RR, Pericak-Vance M, Haines JL, Weiss A, Hauser SL, Oksenberg JR. PTPRC (CD45) is not associated with the development of multiple sclerosis in U.S. patients. Nat Genet. 2001 Sep;29(1):23–24.
Published In
Nat Genet
DOI
ISSN
1061-4036
Publication Date
September 2001
Volume
29
Issue
1
Start / End Page
23 / 24
Location
United States
Related Subject Headings
- United States
- Polymorphism, Genetic
- Point Mutation
- Multiple Sclerosis
- Male
- Leukocyte Common Antigens
- Humans
- Female
- Exons
- Developmental Biology