Linkage analysis in von Recklinghausen neurofibromatosis (NF1) with DNA markers for chromosome 17.
Publication
, Journal Article
Seizinger, BR; Rouleau, GA; Lane, AH; Farmer, G; Ozelius, LJ; Haines, JL; Parry, DM; Korf, BR; Pericak-Vance, MA; Faryniarz, AG
Published in: Genomics
December 1987
The mutant gene causing von Recklinghausen neurofibromatosis (NF1) was recently shown to map to chromosome 17. We have used additional markers for chromosome 17 to narrow further the location of the gene defect. A preliminary multipoint linkage analysis suggests that the NF1 gene is located on the long arm of chroomsome 17, flanked by D17Z1 and NGFR. Linkage analysis with the human oncogene homolog erbA1, which maps to this region, suggests that this cancer-related gene is not the primary cause of NF1.
Duke Scholars
Published In
Genomics
DOI
ISSN
0888-7543
Publication Date
December 1987
Volume
1
Issue
4
Start / End Page
346 / 348
Location
United States
Related Subject Headings
- Receptors, Thyroid Hormone
- Proto-Oncogene Proteins
- Neurofibromatosis 1
- Lod Score
- Humans
- Genetics & Heredity
- Genetic Markers
- Chromosomes, Human, Pair 17
- 3105 Genetics
- 0806 Information Systems
Citation
APA
Chicago
ICMJE
MLA
NLM
Seizinger, B. R., Rouleau, G. A., Lane, A. H., Farmer, G., Ozelius, L. J., Haines, J. L., … Faryniarz, A. G. (1987). Linkage analysis in von Recklinghausen neurofibromatosis (NF1) with DNA markers for chromosome 17. Genomics, 1(4), 346–348. https://doi.org/10.1016/0888-7543(87)90035-8
Seizinger, B. R., G. A. Rouleau, A. H. Lane, G. Farmer, L. J. Ozelius, J. L. Haines, D. M. Parry, B. R. Korf, M. A. Pericak-Vance, and A. G. Faryniarz. “Linkage analysis in von Recklinghausen neurofibromatosis (NF1) with DNA markers for chromosome 17.” Genomics 1, no. 4 (December 1987): 346–48. https://doi.org/10.1016/0888-7543(87)90035-8.
Seizinger BR, Rouleau GA, Lane AH, Farmer G, Ozelius LJ, Haines JL, et al. Linkage analysis in von Recklinghausen neurofibromatosis (NF1) with DNA markers for chromosome 17. Genomics. 1987 Dec;1(4):346–8.
Seizinger, B. R., et al. “Linkage analysis in von Recklinghausen neurofibromatosis (NF1) with DNA markers for chromosome 17.” Genomics, vol. 1, no. 4, Dec. 1987, pp. 346–48. Pubmed, doi:10.1016/0888-7543(87)90035-8.
Seizinger BR, Rouleau GA, Lane AH, Farmer G, Ozelius LJ, Haines JL, Parry DM, Korf BR, Pericak-Vance MA, Faryniarz AG. Linkage analysis in von Recklinghausen neurofibromatosis (NF1) with DNA markers for chromosome 17. Genomics. 1987 Dec;1(4):346–348.
Published In
Genomics
DOI
ISSN
0888-7543
Publication Date
December 1987
Volume
1
Issue
4
Start / End Page
346 / 348
Location
United States
Related Subject Headings
- Receptors, Thyroid Hormone
- Proto-Oncogene Proteins
- Neurofibromatosis 1
- Lod Score
- Humans
- Genetics & Heredity
- Genetic Markers
- Chromosomes, Human, Pair 17
- 3105 Genetics
- 0806 Information Systems