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Prognosis for recurrent stage I malignant melanoma.

Publication ,  Journal Article
Reintgen, DS; Vollmer, R; Tso, CY; Seigler, HF
Published in: Arch Surg
November 1987

The outcome of patients with stage I malignant melanoma has been well assessed in terms of prognostic factors and their effect on survival; however, little is known of the recurrence patterns of cutaneous melanoma or the survival of these patients subsequent to recurrence. A retrospective, computer-aided chart review identified 4185 patients with melanoma who had stage I disease clinically. During a follow-up period of one to 14 years, 35.9% suffered a recurrence. Melanoma of the trunk (37.8%) and head and neck area (46.1%) had an increased incidence of recurrent metastases compared with melanoma of the extremities (29.8%). Local regional metastases accounted for 62.5%, 77.3%, and 85.6% of the recurrences in the head and neck, trunk, and extremity primary sites, respectively, with 65% of the relapses occurring within the first three years. Actuarial five-year survival rates of patients who had recurrent disease were significantly decreased compared with those of patients who had no evidence of metastases during their clinical course. A multivariate analysis was performed to estimate the survival of patients after recurrence. One may use this mathematical model to predict the outcome of individual patients after recurrence and provide a more rationally based prognosis for them and their families.

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Published In

Arch Surg

DOI

ISSN

0004-0010

Publication Date

November 1987

Volume

122

Issue

11

Start / End Page

1338 / 1342

Location

United States

Related Subject Headings

  • Surgery
  • Skin Neoplasms
  • Retrospective Studies
  • Prognosis
  • Neoplasm Recurrence, Local
  • Middle Aged
  • Melanoma
  • Male
  • Humans
  • Female
 

Citation

APA
Chicago
ICMJE
MLA
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Reintgen, D. S., Vollmer, R., Tso, C. Y., & Seigler, H. F. (1987). Prognosis for recurrent stage I malignant melanoma. Arch Surg, 122(11), 1338–1342. https://doi.org/10.1001/archsurg.1987.01400230126022
Reintgen, D. S., R. Vollmer, C. Y. Tso, and H. F. Seigler. “Prognosis for recurrent stage I malignant melanoma.Arch Surg 122, no. 11 (November 1987): 1338–42. https://doi.org/10.1001/archsurg.1987.01400230126022.
Reintgen DS, Vollmer R, Tso CY, Seigler HF. Prognosis for recurrent stage I malignant melanoma. Arch Surg. 1987 Nov;122(11):1338–42.
Reintgen, D. S., et al. “Prognosis for recurrent stage I malignant melanoma.Arch Surg, vol. 122, no. 11, Nov. 1987, pp. 1338–42. Pubmed, doi:10.1001/archsurg.1987.01400230126022.
Reintgen DS, Vollmer R, Tso CY, Seigler HF. Prognosis for recurrent stage I malignant melanoma. Arch Surg. 1987 Nov;122(11):1338–1342.

Published In

Arch Surg

DOI

ISSN

0004-0010

Publication Date

November 1987

Volume

122

Issue

11

Start / End Page

1338 / 1342

Location

United States

Related Subject Headings

  • Surgery
  • Skin Neoplasms
  • Retrospective Studies
  • Prognosis
  • Neoplasm Recurrence, Local
  • Middle Aged
  • Melanoma
  • Male
  • Humans
  • Female