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The effect of indocyanine green pretreatment on the parameters of transscleral diode laser thermotherapy-induced threshold coagulation of the ciliary body.

Publication ,  Journal Article
Kuo, PC; Peyman, GA; Men, G; Bezerra, Y; Torres, F
Published in: Lasers in surgery and medicine
2004

BACKGROUND AND OBJECTIVE: To study the effect of indocyanine green (ICG) pretreatment on threshold parameters of transscleral diode laser thermotherapy-induced threshold coagulation of the ciliary body. The procedure was termed 'cyclothermotherapy' based on the long duration (15-60 seconds) of diode laser application. STUDY DESIGN/MATERIALS AND METHODS: The right eyes of nine young adult New Zealand white rabbits underwent transscleral cyclothermotherapy (TCT, Group 1), TCT following ICG pretreatment (Group 2), and external manipulation of the ciliary body alone (Group 3). Rabbits were sacrificed after 24 hours; specimens were evaluated with gross examination and light microscopy. RESULTS: Thresholds were 30 J/cm2 (TCT) and 4.5 J/cm2 (TCT with ICG). Widespread structural damage was seen in the ciliary processes and the ciliary body in Groups 1 and 2. In Group 3, external manipulation of the ciliary body caused hemorrhage and structural damage confined to the ciliary processes. CONCLUSION: ICG pretreatment reduced the energy necessary to cause a threshold lesion with TCT in nonpigmented rabbits.

Duke Scholars

Published In

Lasers in surgery and medicine

ISSN

0196-8092

Publication Date

2004

Volume

35

Issue

2

Start / End Page

157 / 162

Location

united states

Related Subject Headings

  • Dermatology & Venereal Diseases
  • 3203 Dentistry
  • 3202 Clinical sciences
  • 1103 Clinical Sciences
 

Citation

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Kuo, P. C., Peyman, G. A., Men, G., Bezerra, Y., & Torres, F. (2004). The effect of indocyanine green pretreatment on the parameters of transscleral diode laser thermotherapy-induced threshold coagulation of the ciliary body. Lasers in Surgery and Medicine, 35(2), 157–162.
Kuo, P. C., G. A. Peyman, G. Men, Y. Bezerra, and F. Torres. “The effect of indocyanine green pretreatment on the parameters of transscleral diode laser thermotherapy-induced threshold coagulation of the ciliary body.Lasers in Surgery and Medicine 35, no. 2 (2004): 157–62.
Journal cover image

Published In

Lasers in surgery and medicine

ISSN

0196-8092

Publication Date

2004

Volume

35

Issue

2

Start / End Page

157 / 162

Location

united states

Related Subject Headings

  • Dermatology & Venereal Diseases
  • 3203 Dentistry
  • 3202 Clinical sciences
  • 1103 Clinical Sciences