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Transient late magnetic resonance imaging changes suggesting progression of brain stem glioma: implications for entry criteria for phase II trials.

Publication ,  Journal Article
Longee, DC; Friedman, HS; Djang, WT; Halperin, E; Schold, SC; Oakes, WJ
Published in: Neurosurgery
August 1988

An 8-year-old boy was treated with irradiation (66 Gy) for a brain stem glioma. Five months after the completion of radiotherapy, magnetic resonance imaging demonstrated apparent tumor progression despite the patient's neurological improvement. The child continued to improve, with subsequent radiographic evidence of tumor regression, without additional therapeutic intervention. The evaluations of response and recurrence of brain tumors as well as entry criteria for Phase II studies are discussed.

Duke Scholars

Published In

Neurosurgery

DOI

ISSN

0148-396X

Publication Date

August 1988

Volume

23

Issue

2

Start / End Page

248 / 253

Location

United States

Related Subject Headings

  • Tomography, X-Ray Computed
  • Neurology & Neurosurgery
  • Neurologic Examination
  • Male
  • Magnetic Resonance Imaging
  • Humans
  • Glioma
  • Clinical Trials as Topic
  • Child
  • Brain Stem
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Longee, D. C., Friedman, H. S., Djang, W. T., Halperin, E., Schold, S. C., & Oakes, W. J. (1988). Transient late magnetic resonance imaging changes suggesting progression of brain stem glioma: implications for entry criteria for phase II trials. Neurosurgery, 23(2), 248–253. https://doi.org/10.1227/00006123-198808000-00024
Longee, D. C., H. S. Friedman, W. T. Djang, E. Halperin, S. C. Schold, and W. J. Oakes. “Transient late magnetic resonance imaging changes suggesting progression of brain stem glioma: implications for entry criteria for phase II trials.Neurosurgery 23, no. 2 (August 1988): 248–53. https://doi.org/10.1227/00006123-198808000-00024.
Longee DC, Friedman HS, Djang WT, Halperin E, Schold SC, Oakes WJ. Transient late magnetic resonance imaging changes suggesting progression of brain stem glioma: implications for entry criteria for phase II trials. Neurosurgery. 1988 Aug;23(2):248–53.
Longee, D. C., et al. “Transient late magnetic resonance imaging changes suggesting progression of brain stem glioma: implications for entry criteria for phase II trials.Neurosurgery, vol. 23, no. 2, Aug. 1988, pp. 248–53. Pubmed, doi:10.1227/00006123-198808000-00024.
Longee DC, Friedman HS, Djang WT, Halperin E, Schold SC, Oakes WJ. Transient late magnetic resonance imaging changes suggesting progression of brain stem glioma: implications for entry criteria for phase II trials. Neurosurgery. 1988 Aug;23(2):248–253.
Journal cover image

Published In

Neurosurgery

DOI

ISSN

0148-396X

Publication Date

August 1988

Volume

23

Issue

2

Start / End Page

248 / 253

Location

United States

Related Subject Headings

  • Tomography, X-Ray Computed
  • Neurology & Neurosurgery
  • Neurologic Examination
  • Male
  • Magnetic Resonance Imaging
  • Humans
  • Glioma
  • Clinical Trials as Topic
  • Child
  • Brain Stem